Recruiting

Assistive TechnologyUsing Augmentative & Alternative Communication to Promote Language Recovery for People With Post-Stroke Aphasia

Sponsor:

University of Cincinnati

Code:

NCT04081207

Conditions

Post-stroke Aphasia

Aphasia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

AAC for Language Recovery (AAC-LaRc)

Study Details

Brief summary:

The currently available interventions only partially restore language abilities in patients with post-stroke aphasia; preventing successful reintegration into society. This study will increase our knowledge of how we can use assistive technology interventions to help people with aphasia restore language function. Further, this project will help us identify regions of the brain responsible for these changes.

Conditions

Post-stroke Aphasia

Aphasia

Study ID

NCT04081207

Start date

Sep 1, 2018

Status verified date

Sep, 2019

Completion date

Dec, 2021

Anticipated

Primary completion date

Aug, 2021

Anticipated

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

at least 18 years old
native speaker of american English
compatible for 3 Tesla MRI
Ischemic, left middle cerebral artery stroke
at least 12 months post stroke
pass hearing screening
pass vision screening
diagnosis of aphasia on the Western Aphasia Bedside Screen
ability to produce 5-10 intelligible words
no more than a moderate apraxia of speech or dysarthria
minimal or no AAC/iPad experience
written consent by self or guardian

Exclusion Criteria:

fails to meet the above
Underlying degenerative or metabolic disorder or supervening medical illness
Severe depression or other psychiatric disorder
Report of pregnancy by women of childbearing age

Study Design

Enrollment

20 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: AAC-LaRc

all participants receive the experimental treatment

Interventions

AAC for Language Recovery (AAC-LaRc)

iPads will be programmed with a personalized communication application (app) and a structured 4-step intervention will be employed to instruct patients how to cue themselves during anomic events via pictures, text, or speak buttons.

Primary outcome measure

Western Aphasia Battery-Revised Aphasia Quotient [ Time Frame: 3 years ]
Visual Regions of Interest Activation intensity [ Time Frame: 3 years ]
Connectivity Indices [ Time Frame: 3 years ]

Central Contacts and Locations

Central contacts

Aimee Dietz, PhD

513-558-8551 aimee.dietz@uc.edu

Jennifer Vannest, PhD

513-558-8518 vannesjr@ucmail.uc.edu

Locations

University of Cincinnati

Recruiting

Cincinnati, Ohio, United States, 45267

Contacts

Aimee Dietz, PhD

513-558-8551 aimee.dietz@uc.edu

Jennifer Vannest, BS

513-558-85418 aimee.dietz@uc.edu

Principal Investigator:

Aimee Dietz, PhD

More Information

Sponsor

University of Cincinnati

Last update posted

Sep 9, 2019

Last verified

Sep, 2019

Keywords

augmentative and alternative communication
aphasia
fMRI
DTI
neuroimaging

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Cincinnati on 2019-09-09.