Recruiting

Ablative Radiotherapy

Sponsor:

Duke University

Code:

NCT04085029

Conditions

Oligometastasis

Metastatic Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The purpose of this study is to provide a registry of participants in order to assess the acute adverse event rates following ablative radiotherapy for metastatic disease.

Conditions

Oligometastasis

Metastatic Cancer

Study ID

NCT04085029

Start date

Sep 26, 2019

Status verified date

Feb, 2026

Completion date

Sep, 2029

Anticipated

Primary completion date

Sep, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥ 18 years of age
  • Radiographic evidence of metastatic disease (may include oligoprogression, oligorecurrence or oligometastasis) at the time of study enrollment
  • Planned to receive, currently receiving, or have completed hypofractionated image guided radiotherapy (ablative radiotherapy) to an extracranial site(s)
  • Patient must sign study-specific informed consent

Exclusion Criteria:

• None

Study Design

Enrollment

300 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Occurrence of acute adverse events following radiotherapy [ Time Frame: 90 Days ]

Central Contacts and Locations

Central contacts

Clinical Trials Office

(919) 668 3726RadOnc-Clinical_Trials@dm.duke.edu

Locations

Duke Cancer Institute Cary

Recruiting

Cary, North Carolina, United States, 27518

Contacts

Clinical Trials Office

919-668-3726RadOnc-Clinical_Trials@dm.duke.edu

Durham Veterans Administration Health Care System (DVAHCS)

Recruiting

Durham, North Carolina, United States, 27705

Contacts

Josephine Gaston, RN

josephine.gaston@va.gov

Principal Investigator:

Joseph Salama, MD

Duke University Medical Center

Recruiting

Durham, North Carolina, United States, 27710

Contacts

Clinical Trials Office

919-668-3726RadOnc-Clinical_Trials@dm.duke.edu

Duke Women's Cancer Care Raleigh

Recruiting

Raleigh, North Carolina, United States, 27607

Contacts

Clinical Trials Office

919-668-3726RadOnc-Clinical_Trials@dm.duke.edu

Duke Raleigh Hospital

Recruiting

Raleigh, North Carolina, United States, 27609

Contacts

Clinical Trials Office

919-668-3726RadOnc-Clinical_Trials@dm.duke.edu

More Information

Sponsor

Duke University

Last update posted

Feb 5, 2026

Last verified

Feb, 2026

Keywords

  • Ablative radiotherapy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Duke University on 2026-02-05.