Recruiting

Observational Study

Sponsor:

Mayo Clinic

Code:

NCT04124848

Conditions

Obstructive Sleep Apnea

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The investigators seek to advance the understanding of obstructive sleep apnea as it relates to different ethnic origins as well as sex differences. The investigators will compare Somali patients with known obstructive sleep apnea (OSA) to individuals without OSA, and to individuals of other ethnic/racial origins to determine the risk factors (genetic and/or physiologic) associated with developing cardiovascular diseases. This will help the investigators to understand the unique sleep pathology of individuals of African descent.

Conditions

Obstructive Sleep Apnea

Study ID

NCT04124848

Start date

Oct 25, 2019

Status verified date

Sep, 2025

Completion date

Dec 31, 2031

Anticipated

Primary completion date

Dec 31, 2031

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Self-identify as Somali, African, Asian, and European descent.
  • Adult males and females who are older than 18 years of age.

Exclusion Criteria:

  • Minors under 18 years or adults over 100 years
  • Positive pregnancy

Study Design

Enrollment

600 participants

Anticipated

Interventions and Outcome Measures

Arms

Somali Descent

Study participants who are of Somali origin.

Non-Somali Descent

Study participants who are not of Somali origin.

Primary outcome measure

  • To assess the prevalence of obstructive sleep apnea [ Time Frame: 10 years ]
  • To determine the severity of obstructive sleep apnea [ Time Frame: 10 years ]

Central Contacts and Locations

Central contacts

Somers CPL Lab

507-422-3499CPLSOMALI@mayo.edu

Locations

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

CPL

507-422-3499

Principal Investigator:

Virend Somers, MD, PhD

More Information

Sponsor

Mayo Clinic

Last update posted

Sep 15, 2025

Last verified

Sep, 2025

Keywords

  • Somali-Americans
  • Sleep Disordered Breathing
  • Cardiovascular Diseases
  • Sex and Racial Differences
  • Respiratory Disorders
  • Hypertension
  • Diabetes
  • Health Disparities

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2025-09-15.