Recruiting

Shear Wave Elastography

Sponsor:

University of Alabama at Birmingham

Code:

NCT04144894

Conditions

Acute Kidney Injury

Eligibility Criteria

Sex: All

Age: 19+

Healthy Volunteers: Accepted

Interventions

Shear Wave Elastography

Study Details

Brief summary:

In this exploratory study we explore the use of Shear Wave Elastography to differentiate between Acute Kidney Injury after vascular surgery and among the healthy population.

Conditions

Acute Kidney Injury

Study ID

NCT04144894

Start date

Jan 15, 2020

Status verified date

Sep, 2025

Completion date

Dec 2, 2026

Anticipated

Primary completion date

Oct 15, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 19+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • No history of diabetes or hypertension
  • Estimated Glomerular Filtration Rate > 60 ml/min/m\^2
  • Structurally normal kidney on renal ultrasound
  • BMI < 27 kg/m\^2

Exclusion Criteria:

  • Prisoners directly admitted from a correctional facility
  • Children < 19 years or under 50 kg body weight if age is unknown
  • Patients with end stage renal disease or preexisting glomerular filtration rate less than or equal to 30 mL/min/1.73 m\^2 or need for dialysis
  • Patients with end stage heart disease on the cardiac transplant list
  • Patients undergoing procedures without vascular surgery
  • All transplant patients
  • Patients on ventricular assist devices
  • Patients undergoing emergency procedures
  • Patients with body mass index > 27kg/m\^2
  • Any condition that would impede visualization of the kidneys by ultrasound

Study Design

Enrollment

50 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Diagnostic

Interventions and Outcome Measures

Arms

other: Healthy Controls

other: Vascular Surgery Subjects

Interventions

Shear Wave Elastography

Advanced ultrasound technique

Primary outcome measure

  • Diagnostic factor of Shear Wave Elastography [ Time Frame: From the time of Informed Consent being given to 96 hours after consent being given ]

Central Contacts and Locations

Central contacts

Adam B Sturdivant, MPH

205-934-4042Adamsturdivant@uabmc.edu

Ayesha Bryant, MD, MSPH

205-996-7383Asbryant@uabmc.edu

Locations

University of Alabama at Birmingham

Recruiting

Birmingham, Alabama, United States, 35249

Contacts

Adam Sturdivant, MPH

205-934-4042Adamsturdivant@uabmc.edu

More Information

Sponsor

University of Alabama at Birmingham

Last update posted

Sep 19, 2025

Last verified

Sep, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Alabama at Birmingham on 2025-09-19.