Recruiting

High & Low Adductor Canal Block

Sponsor:

Carilion Clinic

Code:

NCT04155983

Conditions

Osteo Arthritis Knee

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Ropivacaine

Study Details

Brief summary:

The investigators will be comparing the efficacy of two different techniques for performing an adductor canal block to the saphenous nerve as a part of the multimodal pain control regimen for total knee arthroplasty. The investigators will be comparing a "low adductor canal block" in which the surgeon administers local anesthetic to the distal aspect of the nerve from the operative site to a "high adductor canal block" in which the anesthesiologist administers the local anesthetic more proximally along the thigh using ultrasound guidance. The investigators will power the study for non-inferiority to compare the newer "low" block to the more commonly performed and more widely studied "high" block.

Conditions

Osteo Arthritis Knee

Study ID

NCT04155983

Start date

Mar 11, 2020

Status verified date

Oct, 2020

Completion date

Dec 31, 2021

Anticipated

Primary completion date

Dec 30, 2021

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • All patients undergoing unilateral primary TKA for primary osteoarthritis
  • Age over 18

Exclusion Criteria:

  • Pre-operative narcotic use
  • Bilateral procedure
  • Non-Primary arthroplasty
  • Workman's comp
  • Inability to have spinal anesthesia (blood thinners)
  • Unsuccessful spinal anesthesia
  • Inflammatory or Post Traumatic arthritis
  • ASA score of 4
  • Pregnancy

Study Design

Enrollment

140 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: High ACB

In the pre-operative cohort, the adductor canal block is administered by anesthesia staff immediately prior to patient transport to the operating room. The thigh is prepped with cholorhexidine at the midpoint between the anterior superior iliac spine and the patella and sterile drapes are applied. An ultrasound probe is then used to localize the adductor canal and confirm that the femoral artery, femoral vein and saphenous nerve can be visualized deep to the sartorious. The probe is moved proximally or distally until the neurovascular bundle is centered under the sartorius. A 20cc syringe with a blunt tip 1.5in 18ga needle is then used to inject 15cc of 0.5% ropivocaine. Following this, the wound is prepped and draped in usual sterile fashion for the arthroplasty procedure.

active comparator: Low ACB

Surgeon Administered Group In the intra-operative cohort, the block will be administered after the final components are in place and cement debris is removed. The knee joint is irrigated with dilute hibiclens or betadine followed by pulsatile lavage per institutional protocol. A blunt tip 1.5in 18ga needle was then used to administer 15cc of 0.5% ropivocaine.. The location of the saphenous nerve as it exits the adductor canal will be estimated to be 1.5x the TEA proximal to the medial epicondyle in men and 1.3x the TEA proximal in women as described by Kavolus et al. The 60cc of the anesthetic will then injected through the vastus medialis musculature in a field extending from 1cm proximal to one cm distal to the assumed location of the nerve with the needle directed in from 20° to 45° medial. The wound is then irrigated pulsatile lavage one final time and closed in layered fashion.

Interventions

Ropivacaine

The drug will be administered in the same dosage in both arms. The location of the injection will vary by arm.

Primary outcome measure

  • Narcotic Consumption [ Time Frame: Up to 48 hours after surgery ]
  • Narcotic Consumption [ Time Frame: through study completion, an average of 6 weeks ]

Central Contacts and Locations

Locations

Carilion Institute for Orthopaedics & Neurosciences

Recruiting

Roanoke, Virginia, United States, 24014

Contacts

More Information

Sponsor

Carilion Clinic

Last update posted

Oct 30, 2020

Last verified

Oct, 2020

Keywords

  • gonarthrosis
  • osteoarthritis
  • knee
  • total knee arthroplasty
  • adductor canal block
  • saphenous nerve block
  • multimodal pain control

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Carilion Clinic on 2020-10-30.