Recruiting

Resistance Training

Sponsor:

Southern Illinois University Edwardsville

Code:

NCT04163380

Conditions

Women's Health

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Accepted

Interventions

Resistance Training

Study Details

Brief summary:

Although there are numerous studies showing effects of aerobic training on sex hormone concentrations, research analyzing the fluctuation of sex hormones in response to resistance training (RT) is lacking. The objective of this project is to analyze estradiol (E2) and progesterone (P4) responses to an acute resistance training session throughout different phases of the menstrual cycle. This proposed research has strong implications for exercise prescription and for women in general, but more importantly will allow exercise physiologists, coaches, personal trainers, or nutritionists optimize exercise programming around women's menstrual cycle.

Conditions

Women's Health

Study ID

NCT04163380

Start date

Nov 1, 2019

Status verified date

May, 2019

Completion date

Dec, 2021

Anticipated

Primary completion date

Dec, 2021

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Eumenorrheic females
  • Age 18-45 years old
  • BMI of 18.5-34.99 kg/m2

Exclusion Criteria:

  • Practice exercise more than 2 days/week in the last 3 months.
  • Cardiovascular, metabolic, pulmonary or muscular-skeletal condition
  • Taking medications that affect metabolism (e.g. oral contraceptives)
  • Irregular menstrual cycles

Study Design

Enrollment

25 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Early Follicular Phase (EFP)

experimental: Late Follicular Phase (LFP)

experimental: Early Luteal Phase (ELP)

experimental: Late Luteal Phase (LLP)

Interventions

Resistance Training

Participants will exercise at the mid-point of each menstrual cycle phase (EFP- day 4, LFP- day 11, ELP- day 18 and LLP- day 25 for a 28 day menstrual cycle). Training will consist of a warm up. Intensity will be set at 70% of 1RM, and the circuit training will include 7 strength exercises: leg press, rows, back squat, weighted crunches, deadlifts, bench press, and weighted squat jumps. The participant will perform 3 sets f 10 repetitions with 30 seconds of rest

Primary outcome measure

  • Change in estrogen concentrations [ Time Frame: through study completion, an average of 5 weeks ]
  • Change in progesterone concentrations [ Time Frame: through study completion, an average of 5 weeks ]

Central Contacts and Locations

Central contacts

Maria Fernandez del Valle, PhD

6186505905marfern@siue.edu

Locations

Southern Illinois University Edwardsville

Recruiting

Edwardsville, Illinois, United States, 62026

Contacts

Maria Fernandez del Valle, PhD

618-650-5905marfern@siue.edu

Principal Investigator:

Maria Fernandez del Valle, PhD

More Information

Sponsor

Southern Illinois University Edwardsville

Last update posted

Feb 18, 2020

Last verified

May, 2019

Keywords

  • Estrogen
  • Progesterone
  • Menstrual Cycle
  • Resistance Training

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Southern Illinois University Edwardsville on 2020-02-18.