Recruiting

Observational Study

Sponsor:

Canadian Paediatric Society

Code:

NCT04184336

Conditions

Invasive Meningococcal Disease

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Interventions

surveillance

Study Details

Brief summary:

Active metropolitan area surveillance for hospital admissions related to invasive infection with Neisseria meningitidis will be conducted at the 12 centers in the IMPACT network in collaboration with Public Health officials, local infection specialists and infection control practitioners during the interval from January 1, 2016 to December 31, 2022.

Conditions

Invasive Meningococcal Disease

Study ID

NCT04184336

Start date

Jan, 2016

Status verified date

Apr, 2022

Completion date

Dec 31, 2022

Anticipated

Primary completion date

Dec 31, 2022

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:Neisseria meningitidis isolated or detected by PCR from a normally sterile body site or fluid, such as blood, CSF, joint fluid, pleural, peritoneal, pericardial fluid or tissue biopsy -

Exclusion Criteria:patients diagnosed based only on

1. clinical signs, gram stain, or antigen test
2. meningococci isolated only from respiratory tract, including conjunctiva, sinuses, middle ear/mastoid, throat, peritonsillar abscess, cervical lymph node, tracheal aspirate, bronchial lavage etc -

Study Design

Enrollment

400 participants

Anticipated

Interventions and Outcome Measures

Arms

Persons of all ages

Persons of all ages admitted between January 1, 2016 and December 31, 2022 with a positive result of Neisseria meningitidis isolated or detected by PCR from a normal sterile site, such as blood, CSF, joint fluid, pleural, peritoneal, pericardial fluid or tissue biopsy

Interventions

surveillance

Primary outcome measure

  • Laboratory confirmed invasive meningococcal cases. [ Time Frame: End of 2021 ]

Central Contacts and Locations

Central contacts

Melanie Laffin Thibodeau

613-526-9397melaniel@cps.ca

Marie Adele Davis

613-526-9397madavis@cps.ca

Locations

Alberta Children's Hospital

Recruiting

Calgary, Alberta, Canada, T3B 6A8

Principal Investigator:

Taj Jadavji, MD

Stollery Children's Hospital

Recruiting

Edmonton, Alberta, Canada, T6G 1C9

Principal Investigator:

Wendy Vaudry, MD

BC Children's Hospital

Recruiting

Vancouver, British Colombia, Canada, V5Z 4H4

Principal Investigator:

Manish Sadarangani, MD

Children's Hospital Research Institute of Manitoba

Recruiting

Winnipeg, Manitoba, Canada, R3E 3P4

Principal Investigator:

Joanne Embree, MD

Eastern Health Janeway Children's and Rehabilitation Centre

Recruiting

Saint John's, Newfoundland and Labrador, Canada, A1B 3V6

Principal Investigator:

Natalie Bridger, MD

IWK Health Centre

Recruiting

Halifax, Nova Scotia, Canada, B3K6R8

Principal Investigator:

Karina Top, MD

Children's Hospital of Eastern Ontario

Recruiting

Ottawa, Ontario, Canada, K1H 8L1

Principal Investigator:

Nicole Le Saux, MD

The Hospital for Sick Children

Recruiting

Toronto, Ontario, Canada, M5G 1X8

Principal Investigator:

Shaun Morris

CHU- Sainte Justine

Recruiting

Montréal, Quebec, Canada, H3T 1C5

Principal Investigator:

Marc Lebel, MD

Montreal Children's Hospital

Recruiting

Montréal, Quebec, Canada, H4A 3J1

Principal Investigator:

Jesse Papenburg, MD

Centre Mere-Enfant Soleil CHU de Quebec

Recruiting

Québec, Quebec, Canada, G1V 4G2

Principal Investigator:

Roseline Thibeault

Royal University Hospital

Recruiting

Saskatoon, Saskatchewan, Canada, S7N 0W8

Principal Investigator:

Ben Tan, MD

McMaster's Children Hospital

Recruiting

Hamilton, Canada, L8S4K1

More Information

Sponsor

Canadian Paediatric Society

Last update posted

Apr 11, 2022

Last verified

Apr, 2022

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Canadian Paediatric Society on 2022-04-11.