Recruiting

Pharmacogenomic Testing

Sponsor:

University of British Columbia

Code:

NCT04249375

Conditions

Adverse Drug Reaction (ADR)

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

This project addresses the problem of adverse drug reactions in the three most frequently prescribed therapeutic classes of drugs in children: antibiotics, analgesics, and mental health medications.

We will conduct pilot testing of a pharmacogenomic testing panel and study how the tests and generated test results are utilized and understood by physicians, pharmacists, patients and their families.

Conditions

Adverse Drug Reaction (ADR)

Study ID

NCT04249375

Start date

Feb 20, 2020

Status verified date

Apr, 2026

Completion date

Mar, 2028

Anticipated

Primary completion date

Mar, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Participants will be enrolled if they can benefit from pharmacogenomic testing. This means their physician is considering the use of a drug that is part of the panels (analgesics, antibiotics, and mental health medication) or they are already using one.

Exclusion Criteria:

  • Patients who do not speak or understand English.

Study Design

Enrollment

150 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • 150 participants on analgesics, anti-infectives and psychotropics will be given pharmacogenomic recommendations for the risk of gene related adverse events prior to or during treatment. [ Time Frame: June 2020 ]

Central Contacts and Locations

Central contacts

Bruce Carleton, PharmD.

604-875-2179bcarleton@popi.ubc.ca

Locations

Children's and Women's Health Centre of British Columbia

Recruiting

Vancouver, British Columbia, Canada, V6H 3V4

Contacts

Bruce Carleton, PharmD.

604-875-2179bcarleton@popi.ubc.ca

Children's Hospital of Eastern Ontario

Recruiting

Ottawa, Ontario, Canada, K1H 8L1

More Information

Sponsor

University of British Columbia

Last update posted

May 1, 2026

Last verified

Apr, 2026

Keywords

  • Pharmacogenomics
  • Pediatrics
  • Adverse Drug Reactions

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of British Columbia on 2026-05-01.