Recruiting

High Fat Bulletproof Coffee vs. Black Coffee

Sponsor:

University of British Columbia

Code:

NCT04307979

Conditions

Leukocytosis

Triglycerides

Cognitive Function

Inflammatory Response

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Accepted

Interventions

High-fat coffee

Black coffee

Study Details

Brief summary:

This study will determine whether acute ingestion of a high fat "Bulletproof Coffee" will lead to changes in plasma triglycerides, immune cell function, as well as cognitive function when compared to a black coffee.

Conditions

Leukocytosis

Triglycerides

Cognitive Function

Inflammatory Response

Study ID

NCT04307979

Start date

Jan 1, 2020

Status verified date

Mar, 2020

Completion date

Dec 31, 2020

Anticipated

Primary completion date

Dec 31, 2020

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Must be over the age of 18
  • Must drink between 1-4 cups of coffee per day (on average)
  • Must be able to tolerate lactose and dairy products
  • Have not been sick for the past 3 weeks (immune function)
  • Non smoker
  • Must be able to fast for 10-12 hours

Exclusion Criteria:

  • If you are required to take corticosteroids (immune function)
  • Cannot understand or speak English
  • Individual has an auto-immune disease and requires medication
  • Individual is following a ketogenic diet
  • Individual has allergy or sensitivity to dairy, coffee or caffeine or coconut oil
  • Individual has hypertension

Study Design

Enrollment

20 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Bulletproof Coffee

A black coffee (bullet proof coffee keurig pod) with 29 grams of added fat (1 tablespoon bullet proof brain octane medium chain triglyceride oil, and 1 tablespoon bullet proof grass fed ghee) blended for 20 seconds with butter scent that is added to the lid.

placebo comparator: Black Coffee

Black coffee that is blended for 20 seconds with butter scent added to the top of the lid.

Interventions

High-fat coffee

A high fat coffee that consists of 29 grams of added fat from grass fed ghee, and MCT oil.

Black coffee

A regular black coffee with no added caloric content.

Primary outcome measure

  • Plasma triglycerides [ Time Frame: Change over 3 hours following beverage consumption ]

Central Contacts and Locations

Central contacts

Garett S Jackson, B.H.K

1-250-807-9122garett11@mail.ubc.ca

Jonathan P Little, PhD

1-250-878-6893jonathan.little@ubc.ca

Locations

University of British Columbia, Okanagan.

Recruiting

Kelowna, British Columbia, Canada, V1V 1V7

Contacts

Jonathan P Little, PHD

1-250-878-6893jonathan.little@ubc.ca

Garett S Jackson, B.H.K

1-250 807 9122garett11@mail.ubc.ca

More Information

Sponsor

University of British Columbia

Last update posted

Mar 13, 2020

Last verified

Mar, 2020

Keywords

  • Triglycerides
  • Leukocyte
  • Monocyte
  • Neutrophil
  • Activation
  • High-fat

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of British Columbia on 2020-03-13.