Recruiting

Observational Study

Sponsor:

The Cleveland Clinic

Code:

NCT04310241

Conditions

Amblyopia

Strabismus

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Patching therapy, Glasses

Study Details

Brief summary:

Amblyopia and strabismus are characterized by a reduction in visual acuity, contrast sensitivity, grating acuity, vernier acuity, reading difficulties and binocular visual function deficits. Treated patients have residual visual function deficits. The purpose of the current study is to quantify various visual functions in amblyopic and strabismic participants at baseline, during and at the completion of treatment.

Conditions

Amblyopia

Strabismus

Study ID

NCT04310241

Start date

Feb 21, 2020

Status verified date

Mar, 2026

Completion date

Mar 12, 2027

Anticipated

Primary completion date

Mar 12, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • History of amblyopia or presence of amblyogenic risk factors.

Exclusion Criteria:

  • History of neurologic disorders

Study Design

Enrollment

150 participants

Anticipated

Interventions and Outcome Measures

Arms

Control subjects

Subjects who state they have no eye or neurologic problems or disease other than perhaps wearing glasses or contact lenses and upon review of medical history.

Amblyopia

Clinical diagnosis of amblyopia

Interventions

Patching therapy, Glasses

Patching, glasses and strabismus surgery are commonly employed measures in treatment of amblyopia and strabismus.

Primary outcome measure

  • Visual Functions [ Time Frame: 0-3 years depending on duration of treatment ]
  • Visual Functions [ Time Frame: 0-3 years depending on duration of treatment ]
  • Visual functions [ Time Frame: 0-3 years depending on duration of treatment ]
  • Visual functions [ Time Frame: 0-3 years depending on duration of treatment ]
  • Visual functions [ Time Frame: 0-3 years depending on duration of treatment ]
  • Visual functions [ Time Frame: 0-3 years depending on duration of treatment ]
  • Visual functions [ Time Frame: 0-3 years depending on duration of treatment ]

Central Contacts and Locations

Central contacts

Kimberly Baynes, MSN

216-444-2566baynesk@ccf.org

Locations

Cleveland Clinic

Recruiting

Cleveland, Ohio, United States, 44195

Contacts

Fatema Ghasia, MD

216 318 7809

Kimberly Baynes

2164442566baynesk@ccf.org

More Information

Sponsor

The Cleveland Clinic

Last update posted

Mar 4, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by The Cleveland Clinic on 2026-03-04.