Recruiting

Observational Study

Sponsor:

Columbia University

Code:

NCT04367857

Conditions

Covid-19

Coronavirus Infection

Coronavirus

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

COVID-19 Serology

Health Care Worker Survey

Study Details

Brief summary:

The novel coronavirus (SARS-CoV-2) has spread all around the world and testing has posed a challenge globally. Health care providers are highly exposed and are an important group to test. On top of these concerns, health care workers are also stressed by the needs on responders in the COVID-19 crisis. The investigators will look at different ways to measure how common COVID-19 is among health care workers, how common is the presence of antibodies by serological tests (also known as serostatus). The investigators will describe health worker mental and emotional well-being and their coping strategies in their institutional settings. Lastly, the investigators will describe how knowing serostatus can affect individuals' mental and emotional well-being and how to cope in the midst of the COVID-19 response. This will help to how to better test and help healthcare workers in the COVID-19 pandemic and prepare for possible future outbreaks.

Conditions

Covid-19

Coronavirus Infection

Coronavirus

Study ID

NCT04367857

Start date

Apr 18, 2020

Status verified date

Apr, 2026

Completion date

Feb, 2027

Anticipated

Primary completion date

Feb, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 18 years of age or older
  • NewYork-Presbyterian (NYP) healthcare personnel employee or affiliate
  • Understands and reads English

Exclusion Criteria:

  • Younger than 18 years of age
  • Mentally and/or physically unable to complete study requirements

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Arms

Prior Positive polymerase chain reaction (PCR) and Recovered

Prior Positive PCR result, fully recovered, back at work and symptom free for greater than or equal than 14 days.

Never tested, history of COVID-19 Symptoms and Recovered

Never tested and history of COVID-19 symptoms and symptom-free for more than 14 days

Never tested and current COVID-19 Symptoms

Never tested and current COVID-19 Symptoms (e.g. referred by a provider or clinic)

Never tested and asymptomatic

Never tested and asymptomatic for COVID-19 symptoms, including asymptomatic health care worker

Interventions

COVID-19 Serology

Quantitate Serology enzyme-linked immunosorbent assay (ELISA) for COVID-19

Health Care Worker Survey

The purpose of this survey is to assess how healthcare workers are experiencing and coping with the COVID-19 crisis.

Primary outcome measure

  • Proportion seropositive [ Time Frame: Up to 12 months after collection visit ]

Central Contacts and Locations

Central contacts

Locations

NewYork-Presbyterian Hosptial/Columbia University Irving Medical Center

Recruiting

New York, New York, United States, 10032

More Information

Sponsor

Columbia University

Last update posted

Apr 8, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Columbia University on 2026-04-08.