Recruiting

TAP Block

Sponsor:

Western Michigan University School of Medicine

Code:

NCT04382859

Conditions

Pain, Postoperative

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Interventions

Transversus abdominis plane (TAP) block with liposomal bupivacaine

Study Details

Brief summary:

Our goal is to determine if liposomal bupivacaine compared to standard bupivacaine results in increased pain control and decreased narcotic pain medication use when used in TAP blocks prior to laparoscopic hysterectomies for benign indications.

Conditions

Pain, Postoperative

Study ID

NCT04382859

Start date

Dec 1, 2020

Status verified date

Nov, 2020

Completion date

Feb, 2021

Anticipated

Primary completion date

Dec, 2020

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Women undergoing non robotic assisted laparoscopic surgery for benign gynecologic conditions
  • English speaking

Exclusion Criteria:

  • Known current malignancy
  • Contraindication to medications

Study Design

Enrollment

56 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

active comparator: TAP block with liposomal bupivacaine

Active comparator

other: TAP block with 0.25% bupivacaine

Standard comparator

Interventions

Transversus abdominis plane (TAP) block with liposomal bupivacaine

Transversus abdominis plane (TAP) blocks are safe and effective procedures for the provision of postoperative pain management following abdominal procedures (3) and have been widely used across specialties with reduction in postoperative pain and narcotic use (4-7).

Primary outcome measure

  • Pain rating 1 hour post operation [ Time Frame: 1 hour post operation ]
  • Pain rating 2 hours post operation [ Time Frame: 2 hours post operation ]
  • Pain rating 4 hours post operation [ Time Frame: 4 hours post operation ]
  • Pain rating 72 hours post operation [ Time Frame: 72 hours post operation ]

Central Contacts and Locations

Central contacts

Melinda Abernethy, MD

(919) 260-9328melinda.abernethy@med.wmich.edu

Locations

Bronson Methodist Hospital

Recruiting

Kalamazoo, Michigan, United States, 49007

Contacts

Melinda Abernethy, MD

919-260-9328melnda.abernethy@med.wmich.edu

More Information

Sponsor

Western Michigan University School of Medicine

Last update posted

Nov 27, 2020

Last verified

Nov, 2020

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Western Michigan University School of Medicine on 2020-11-27.