Recruiting

EUS-CPN

Sponsor:

Indiana University

Code:

NCT04403074

Conditions

Chronic Pancreatitis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Celiac Plexus Neurolysis

Study Details

Brief summary:

Physicians need a tracking system for specific treatment modalities, and data to determine the impact of endoscopic ultrasound pain management for patients with chronic pancreatitis.

Conditions

Chronic Pancreatitis

Study ID

NCT04403074

Start date

Oct 20, 2017

Status verified date

Feb, 2026

Completion date

Oct 20, 2029

Anticipated

Primary completion date

Oct 20, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 18 years of age or older
  • Referral for the treatment of pain related to chronic pancreatitis

Exclusion Criteria:

  • Less than 18 years of age
  • Absence of chronic pancreatitis

Study Design

Enrollment

35 participants

Anticipated

Interventions and Outcome Measures

Arms

Chronic Pancreatitis Patients

Patients that have Chronic Pancreatitis and the current treatment with Celiac Plexus Blocks (CPB) are providing minimal relief of pain (CPB provide less than one month of pain relief). These patient will then receive a Celiac Plexus Neurolysis.

Interventions

Celiac Plexus Neurolysis

When CPBs are not effective (less than one month of relief) then a Celiac Plexus Neurolysis may be completed to manage pain associated with Chronic Pancreatitis.

Primary outcome measure

  • Use of Pain medication [ Time Frame: Immediately post procedure & weekly up to 24 weeks ]
  • Patient's pain intensity score (numeric pain rating scale using the visual analogue scale VAS from 1-10) will be assessed weekly (via phone call follow ups) starting right after CPN and continuing for 24 weeks. [ Time Frame: Immediately post procedure and weekly up to 24 weeks ]
  • Dosage of pain medication [ Time Frame: Immediately post procedure and weekly up to 24 weeks ]

Central Contacts and Locations

Central contacts

Mohammad Al-Haddad

3179440980moalhadd@iu.edu

Locations

Indiana University Hospital

Recruiting

Indianapolis, Indiana, United States, 46202

Contacts

Mohammad Al-Haddad

3179440980moalhadd@iu.edu

More Information

Sponsor

Indiana University

Last update posted

Feb 18, 2026

Last verified

Feb, 2026

Keywords

  • Pancreatitis
  • Indiana
  • Block
  • Celiac
  • Plexus

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-19. This information was provided to ClinicalTrials.gov by Indiana University on 2026-02-18.