Recruiting

Physical Activity

Sponsor:

Science and Research Centre Koper

Code:

NCT04410055

Conditions

Diabete Mellitus

Aging

Cognitive Change

Eligibility Criteria

Sex: All

Age: 65 - 70+

Healthy Volunteers: Not accepted

Interventions

Sitting

Static standing

Dynamic standing

Study Details

Brief summary:

Physical inactivity is prevalent in older adults and poses a risk factor for the development of type 2 diabetes. The aim of this pilot study was to examine the effect of non-exercise physical activity using a standing desk on clinical variables in older adults with type 2 diabetes.

Conditions

Diabete Mellitus

Aging

Cognitive Change

Study ID

NCT04410055

Start date

Jan 8, 2012

Status verified date

May, 2020

Completion date

Jan 8, 2022

Anticipated

Primary completion date

Jan 8, 2022

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 65 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • older participants (65+ years) with clinically confirmed type 2 diabetes
  • Body mass index above 25 and less than 40 kg/m2

Exclusion Criteria:

  • participants unable to perform a short clinical and motor function test battery (sABC test, Mini-BEST)

Study Design

Enrollment

120 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Sitting

Three hours of sitting condition with ad-libitum breaks for toilet use and stretching. During this condition all cognitive, motor and pain scales were monitored.

active comparator: Static standing

Four hours of static standing condition with ad-libitum breaks for toilet use and stretching. During this condition all cognitive, motor and pain scales were monitored.

active comparator: Dynamic standing

Four hours of dynamic standing condition with ad-libitum breaks for toilet use and stretching. During this condition all cognitive, motor and pain scales were monitored.

Interventions

Sitting

We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification. To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing. Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)

Static standing

We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification. To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing. Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)

Dynamic standing

We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification. To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing. Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)

Primary outcome measure

  • Oxygen consumption [ Time Frame: change in oxygen consumption between all three conditions, which will be measured with a minimum washout period of 3 days ]

Central Contacts and Locations

Central contacts

Nicolaas Bohnen, MD, PhD

nbohnen@med.umich.edu

Locations

University of Michigan

Recruiting

Ann Arbor, Michigan, United States, 48104

Contacts

More Information

Sponsor

Science and Research Centre Koper

Last update posted

Jun 1, 2020

Last verified

May, 2020

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Science and Research Centre Koper on 2020-06-01.