Recruiting

Cardiovascular Protocol

Sponsor:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Code:

NCT04464655

Conditions

Coronary Artery Disease

Myocarditis

Infiltrative Cardiomyopathy

Dilated Cardiomyopathy

Hypertrophic Cardiomyopathy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

This study aims to identify and assess new CMR techniques that can improve current CMR protocols.

Conditions

Coronary Artery Disease

Myocarditis

Infiltrative Cardiomyopathy

Dilated Cardiomyopathy

Hypertrophic Cardiomyopathy

Study ID

NCT04464655

Start date

Dec 12, 2019

Status verified date

Oct, 2024

Completion date

Jan 31, 2025

Anticipated

Primary completion date

Nov 30, 2024

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Healthy Volunteers

Inclusion Criteria:

  • Age: > 18y, Informed consent No known current or pre-existing significant medical conditions that would affect the cardiovascular or respiratory system

Exclusion Criteria:

  • General MRI contraindications: MR- incompatible devices such as pacemakers, defibrillators, or implanted material or foreign bodies. Consumption of caffeinated drinks or foods (including cocoa and chocolate) during the 12 hours prior to the exam.Regular nicotine consumption during the last 6 months

Patients

Inclusion Criteria:

  • Age: >18 y, Informed consent, Clinically indicated CMR exam

Exclusion Criteria:

  • General MRI contraindications: MR- incompatible devices such as pacemakers, defibrillators, or implanted material or foreign bodies Vasoactive medication (e.g. nitro) during the 12 hours prior to the exam. Consumption of caffeinated drinks or foods (including cocoa and chocolate) during the 12 hours prior to the exam.

Regular nicotine consumption during the last 6 months

Study Design

Enrollment

2130 participants

Anticipated

Interventions and Outcome Measures

Arms

Healthy Volunteers

Age: >18 y, No known current or pre-existing medical conditions that would affect the cardiovascular or respiratory system.

Patients

Age: > 18y, Clinically indicated CMR exam

Primary outcome measure

  • Primary diagnosis comparison between SMART CMR and standard CMR [ Time Frame: 2019-2025 ]
  • Main finding comparison between SMART CMR and standard CMR in patients with suspected coronary artery disease [ Time Frame: 2019-2025 ]

Central Contacts and Locations

Central contacts

Elizabeth Konidis

514-934-1934elisavet.konidis@muhc.mcgill.ca

Adonis Rodaros

514-934-1934adonis.rodaros@muhc.mcgill.ca

Locations

McGill University Health Center

Recruiting

Montreal, Quebec, Canada, H4A 3J1

Contacts

Matthias G Friedrich, MD

514-934-1934matthias.friedrich@mcgill.ca

Elizabeth Konidis

514-934-1934elisavet.konidis@muhc.mcgill.ca

More Information

Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Last update posted

Oct 24, 2024

Last verified

Oct, 2024

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by McGill University Health Centre/Research Institute of the McGill University Health Centre on 2024-10-24.