Recruiting

Observational Study

Sponsor:

Johns Hopkins University

Code:

NCT04473794

Conditions

Pancreatic Neoplasms

Pancreas Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The aims of this study are to determine the natural history of pancreatic cysts and to propose and prospectively validate a diagnostic approach and model for prediction of mucinous versus non-mucinous, and malignant versus non-malignant, pancreatic cysts using a combination of clinical, radiologic, and biomarker characteristics.

Conditions

Pancreatic Neoplasms

Pancreas Cancer

Study ID

NCT04473794

Start date

Jul 20, 2022

Status verified date

Feb, 2026

Completion date

Aug 1, 2036

Anticipated

Primary completion date

Nov 1, 2035

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adult patients age 18 years and older
  • Referred for assessment of a pancreatic cyst.

Exclusion Criteria:

  • Medically ill patients with American Society of Anesthesiologists class 4 or greater.
  • Inability to provide informed consent.
  • Pregnancy or lactation.

Study Design

Enrollment

5000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Clinical utility of Compcyst in pancreatic cysts as assessed by patient chart review [ Time Frame: 15 years ]

Central Contacts and Locations

Central contacts

Elham Afghani, MD MPH

410-614-6708eafghan1@jhmi.edu

Locations

The Johns Hopkins Hospital

Recruiting

Baltimore, Maryland, United States, 21287

Contacts

Elham Afghani, MD MPH

410-614-6708eafghan1@jhmi.edu

Vaishnavi S Sawant, MBBS MPH

443-603-5875vsawant1@jh.edu

More Information

Sponsor

Johns Hopkins University

Last update posted

Mar 2, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Johns Hopkins University on 2026-03-02.