Recruiting
Phase 1

Chemotherapy & Cellular Immunotherapy

Sponsor:

City of Hope Medical Center

Code:

NCT04510051

Conditions

Malignant Brain Neoplasm

Recurrent Malignant Brain Neoplasm

Refractory Malignant Brain Neoplasm

Eligibility Criteria

Sex: All

Age: 4 - 25

Healthy Volunteers: Not accepted

Interventions

Cyclophosphamide

Fludarabine

IL13Ralpha2-specific Hinge-optimized 41BB-co-stimulatory CAR Truncated CD19-expressing Autologous T-Lymphocytes

Study Details

Eligibility Criteria

Study Design

Interventions and Outcome Measures

Central Contacts and Locations

More Information

Trial information was received from ClinicalTrials.gov and was last updated on 2026-02-13. This information was provided to ClinicalTrials.gov by City of Hope Medical Center on 2025-10-06.