Recruiting

Nano-Based Analgesics

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT04533919

Conditions

Spinal Cord Neoplasm

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Study Details

Brief summary:

This study investigates the pre-clinical nano-based analgesics in cells from human dorsal root ganglia (clusters of neurons). Collecting these neurons may help future research related to safe and effective pain treatment.

Conditions

Spinal Cord Neoplasm

Study ID

NCT04533919

Start date

Jun 16, 2020

Status verified date

Oct, 2025

Completion date

Apr 30, 2027

Anticipated

Primary completion date

Apr 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

---All patients undergoing surgery to resect spinal tumors

Exclusion Criteria:

---None

Study Design

Enrollment

8 participants

Anticipated

Interventions and Outcome Measures

Arms

Basic science (dorsal root ganglia collection)

Patients' leftover dorsal root ganglia samples are collected during standard of care surgery.

Interventions

Biospecimen Collection

Undergo collection of dorsal root ganglia

Primary outcome measure

  • Viability assays [ Time Frame: 3 years ]
  • Functional assays [ Time Frame: 3 years ]

Central Contacts and Locations

Central contacts

Andrew J. Shepherd

713-745-7959ajshepherd@mdanderson.org

Locations

M D Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Andrew J. Shepherd

713-745-7959

Principal Investigator:

Andrew J. Shepherd

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Oct 14, 2025

Last verified

Oct, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2025-10-14.