Recruiting

Virtual Reality

Sponsor:

McGill University

Code:

NCT04559373

Conditions

Stroke

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Virtual Reality and Field Training (VRFT)

Study Details

Brief summary:

While stroke survivors discharged from rehabilitation present with some recovery in mobility, their ability to ambulate in the community remains limited. The investigators propose to test a novel, low-cost, intensive and individually tailored intervention that combines virtual reality (VR) and field training to enhance community ambulation and participation in stroke survivors discharged from rehabilitation.

The aims are to: (1) Assess feasibility, acceptability, safety and adherence of the intervention in stroke survivors; and (2) Examine the extent to which post-intervention changes in functional walking and participation to community walking vary according to walking, cognitive and visual-perceptual abilities.

The investigators will use a virtual environment prototype simulating a shopping mall and surrounding streets, in which participants will interact using VR goggles and game controllers. Scenarios of increasing levels of complexity will be introduced. This intervention study involves a single group, multiple pre- multiple post- study design where chronic stroke participants will engage in a 4-week training program. The program will include VR training sessions performed in the clinical setting (3/week) and practice of community ambulation skills while supervised by family/caregivers (2/week). Participants will be assessed on measures of functional walking, balance \& mobility and participation to community walking. Adherence, safety and acceptability will be documented. This study will generate foundation knowledge on the response to the intervention based on individual capacities.

Conditions

Stroke

Study ID

NCT04559373

Start date

Apr 1, 2021

Status verified date

Feb, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

May 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

People with chronic stroke and persistent deficits in walking / visual-perceptual / cognitive capacities. They can be male or female, aged from 40 to 74 years, with normal/corrected visual and auditory acuity, and present with:

  • First-ever supratentorial unilateral stroke 9-24 months ago (such chronicity will ensure steady-state mobility without long-term disuse-related changes
  • Mild-to-moderate hemiparesis (Chedoke McMaster Stoke Assessment stages 4/7-6/7 on postural control, leg \& foot)
  • Ability to walk independently with/without walking aids for at least 1 min at 0.4-0.9 m/s (such a speed range indicates mobility not sufficient for functional community ambulation: shopping \~1.1m/s, street crossing \~1.2 m/s)
  • Intact or mildly affected cognitive function (Montreal Cognitive Assessment scores ≥ 22/30)
  • Intact to moderately affected visual-perceptual function (positive scores on a maximum of 3/6 tasks on the Behavioural Inattention Test)

Exclusion Criteria:

  • Subjects with comorbidities interfering with walking
  • Subjects with comorbidities interfering with visual perception
  • Subjects without medical clearance for exercise

Study Design

Enrollment

40 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Virtual Reality and Field Practice Training (VRFT)

Participants will engage in a 4-week VRFT intervention that comprises of 1-hour training sessions, 3 times/week.

Interventions

Virtual Reality and Field Training (VRFT)

The VRFT intervention involves the intensive practice of community ambulation skills. Some of the training sessions will be performed in a virtual environment, while others will consist of field training exercises in the community. During the intervention, stroke participants will be invited to practice different dimensions of community ambulation, such as postural transitions, avoiding other pedestrians, dual-task walking, etc.

Primary outcome measure

  • Post-intervention change in the Six Minute Walk Test (6MWT) [ Time Frame: Pre-intervention (Week4) and post-intervention (Week8) ]
  • Change in the Six Minute Walk Test (6MWT) at Follow-up [ Time Frame: Post-intervention (Week8) and Follow-up (Week12) ]

Central Contacts and Locations

Central contacts

Locations

Jewish Rehabilitation Hospital

Recruiting

Laval, Quebec, Canada, H7V1R2

Contacts

More Information

Sponsor

McGill University

Last update posted

Feb 20, 2026

Last verified

Feb, 2026

Keywords

  • Aging
  • Biomechanics
  • Community ambulation
  • Intervention
  • Locomotion
  • Rehabilitation
  • Sensorimotor integration
  • Virtual reality

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by McGill University on 2026-02-20.