Recruiting

Observational Study

Sponsor:

Ohio State University Comprehensive Cancer Center

Code:

NCT04567706

Conditions

Melanoma

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Interventions

Biospecimen Collection

Study Details

Brief summary:

This study collects and stores blood and tumor samples from patients with malignant melanoma and healthy individuals. The purpose of this study is to gain a better understanding of the causes of melanoma and how melanoma tumors behave. Storing blood and tumor samples for future research may lead to new discoveries that may ultimately help with diagnosing or treating this disease.

Conditions

Melanoma

Study ID

NCT04567706

Start date

May 7, 2013

Status verified date

Feb, 2026

Completion date

Oct 31, 2027

Anticipated

Primary completion date

Oct 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Patient with malignant melanoma or personal history of melanoma
  • Normal donors
  • Informed consent can be obtained
  • Patients with any stage of malignant melanoma

Exclusion Criteria:

  • Incarcerated individuals will be excluded from this protocol

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Arms

Ancillary-correlative (biospecimen collection)

Patients undergo collection of blood samples at the time of the initial diagnostic work-up, and possibly prior to the initiation of surgery, chemotherapy, immunotherapy, or radiation therapy, at tumor progression or recurrence, and annually during routine follow-up (no more than 4 blood draws per year). Patients may also undergo collection of tissue sample during standard of care surgical or radiologic procedures. Healthy individuals undergo collection of blood samples up to 4 times over 1 year.

Interventions

Biospecimen Collection

Undergo collection of blood and tissue samples

Primary outcome measure

  • New prognostic markers in malignant melanoma [ Time Frame: Up to 3 months ]

Central Contacts and Locations

Central contacts

The Ohio State University Comprehensive Cancer Center

800-293-5066OSUCCCClinicaltrials@osumc.edu

Locations

Ohio State University Comprehensive Cancer Center

Recruiting

Columbus, Ohio, United States, 43210

Contacts

William E. Carson, MD

614-293-6306

Principal Investigator:

William E. Carson, MD

More Information

Sponsor

Ohio State University Comprehensive Cancer Center

Last update posted

Feb 17, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Ohio State University Comprehensive Cancer Center on 2026-02-17.