Recruiting

Immunity Measurement

Sponsor:

Stanford University

Code:

NCT04579588

Conditions

Corona Virus Infection

Flu Vaccine

Immunity

Eligibility Criteria

Sex: All

Age: 9 - 64

Healthy Volunteers: Accepted

Interventions

Flu shot

Study Details

Brief summary:

The purpose of this study is to measure immunity to the flu vaccine over time in patients who have had COVID-19 and may have other medical conditions including obesity, type 2 diabetes, chronic fatigue, or long-term COVID-19 symptoms. Adults and children (age 9 to 64) who had been diagnosed with COVID-19 as well as controls without COVID-19 will be invited to participate in this study.

Conditions

Corona Virus Infection

Flu Vaccine

Immunity

Study ID

NCT04579588

Start date

Oct 29, 2020

Status verified date

Nov, 2025

Completion date

Apr, 2028

Anticipated

Primary completion date

Apr, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 9 - 64

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Age 9 through 64 years
  • Diagnosed with COVID-19 at least 2 months prior enrollment
  • Patients with or without obesity, diabetes, chronic fatigue and/or long term COVID-19 symptoms
  • Patients without COVID-19 diagnosis for controls

Exclusion Criteria:

  • Received the influenza vaccine less than 4 months ago
  • Pregnant or lactating
  • Patients with special risks attendant to venipuncture
  • Use of immunomodulatory medications that may impact vaccine immune response per clinician's judgment
  • Contraindication to the flu vaccine
  • Immunodeficiency or autoimmune disease that may impact vaccine immune responses per clinician's judgement

Study Design

Enrollment

230 participants

Anticipated

Interventions and Outcome Measures

Arms

COVID-19 participants

Control participants

Interventions

Flu shot

All participants will receive a single shot of the flu vaccine

Primary outcome measure

  • Testing immunity to the flu vaccine over time [ Time Frame: 1 week ]
  • Testing immunity to the flu vaccine over time [ Time Frame: 1 month ]

Central Contacts and Locations

Central contacts

SNP Center Inquiry

(650) 521-7237snpcenterallergy_inquiry@stanford.edu

Locations

Stanford University

Recruiting

Palo Alto, California, United States, 94304

Contacts

SNP Center Inquiry

(650) 521-7237snpcenterallergy_inquiry@stanford.edu

More Information

Sponsor

Stanford University

Last update posted

Mar 18, 2026

Last verified

Nov, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Stanford University on 2026-03-18.