Recruiting

Observational Study

Sponsor:

Beth Israel Deaconess Medical Center

Code:

NCT04603196

Conditions

Multiple Sclerosis

Obstructive Sleep Apnea

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

This study will evaluate the influence of sleep apnea on clinical and radiological features of MS. Sleep apnea is associated with hypoxemia during sleep, which is likely detrimental to MS. Clinical data (MRI, lab results, medical history, labs, and sleep studies) of MS patients will be collected and analyzed. This will be done to study correlations between MRI, clinical data, lab studies and sleep studies. There is specific interest in the type of sleep apnea associated with MS, and whether MRI or clinical metrics of MS severity correlate with presence or absence of sleep apnea.

Conditions

Multiple Sclerosis

Obstructive Sleep Apnea

Study ID

NCT04603196

Start date

Jun 20, 2019

Status verified date

May, 2026

Completion date

Jun 20, 2030

Anticipated

Primary completion date

Jun 20, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Written consent
  • Over age 18
  • Confirmed diagnosis of multiple sclerosis

Exclusion Criteria:

  • cannot provide informed consent

Study Design

Enrollment

800 participants

Anticipated

Interventions and Outcome Measures

Arms

Patients with Multiple Sclerosis with obstructive sleep apnea

Patients with Multiple Sclerosis with obstructive sleep apnea

Patients with MS without obstructive sleep apnea

Patients with MS without obstructive sleep apnea

Primary outcome measure

  • Home Sleep Study Data [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Locations

Beth Israel Deaconess Medical Center

Recruiting

Boston, Massachusetts, United States, 02215

Contacts

Principal Investigator:

Jacob Sloane, MD, PhD

More Information

Sponsor

Beth Israel Deaconess Medical Center

Last update posted

May 11, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Beth Israel Deaconess Medical Center on 2026-05-11.