Recruiting

Neoadjuvant Chemotherapy

Sponsor:

Northwestern University

Code:

NCT04616131

Conditions

Pancreas Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

For patients who have been diagnosed with pancreatic cancer that has not spread outside of the pancreas and nearby lymph nodes. The purpose of this research study is to understand if we are able to detect pancreatic cancer DNA in the blood stream before, during, and after treatment.

Conditions

Pancreas Cancer

Study ID

NCT04616131

Start date

Oct 1, 2020

Status verified date

Jun, 2026

Completion date

Oct 1, 2029

Anticipated

Primary completion date

Oct 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Biopsy or cytology proven adenocarcinoma of the pancreas
  • No clinical evidence of metastatic disease on imaging
  • Age 18 or older
  • Receiving chemotherapy for non-metastatic pancreatic cancer

Exclusion Criteria:

  • Biopsy proven metastatic disease

Study Design

Enrollment

500 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Number of patients with circulating tumor DNA (ctDNA) levels as not detectable in their blood compared to number of patients with ctDNA detected. [ Time Frame: 3 months ]

Central Contacts and Locations

Central contacts

Study Coordinator

3126951301cancertrials@northwestern.edu

Donald Smith, MS

630-352-5360Donald.Smith3@nm.org

Locations

Northwestern Medicine Cancer Center Kishwaukee

Recruiting

DeKalb, Illinois, United States, 60115

Contacts

Donald Smith

630-352-5360Donald.Smith3@nm.org

Northwestern Medicine Cancer Center Delnor

Recruiting

Geneva, Illinois, United States, 60135

Contacts

Donald Smith

630-352-5360donald.smith3@nm.org

Northwestern Medicine Cancer Center Warrenville

Recruiting

Warrenville, Illinois, United States, 60555

Contacts

Akhil Chawla, MD

630-352-5353Akhil.Chawla@nm.org

More Information

Sponsor

Northwestern University

Last update posted

Jun 18, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Northwestern University on 2026-06-18.