Recruiting

Observational Study

Sponsor:

Henry Ford Health System

Code:

NCT04623424

Conditions

Stem Cell Transplant Complications

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

intestinal microbiota

Study Details

Brief summary:

In this prospective study, the primary objective will be to investigate the association between the use of antibiotics administered during the admission period of Stem cell transplant (SCT) and the rate of overall change in microbiota composition across adjacent samples in time.

Conditions

Stem Cell Transplant Complications

Study ID

NCT04623424

Start date

Nov 3, 2020

Status verified date

Feb, 2026

Completion date

Nov 3, 2028

Anticipated

Primary completion date

Nov 3, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients aged 18-80 years
  • patients undergoing allogenic or autologous SCT for malignant hematological conditions or bone marrow failure

Study Design

Enrollment

255 participants

Anticipated

Interventions and Outcome Measures

Interventions

intestinal microbiota

Stoll samples will be tested for different bacteria

Primary outcome measure

  • Changes in microbiome [ Time Frame: Up to 6 months post stem cell transplant ]

Central Contacts and Locations

Central contacts

shatha farhan, MD

313 916 5002SFARHAN1@HFHS.ORG

Locations

Henry Ford Health System

Recruiting

Detroit, Michigan, United States, 48202

Contacts

shatha farhan

313-916-5002sfarhan1@hfhs.org

More Information

Sponsor

Henry Ford Health System

Last update posted

Feb 24, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Henry Ford Health System on 2026-02-24.