Recruiting

Chromosomal Screening

Sponsor:

Olive Fertility Centre

Code:

NCT04732013

Conditions

Infertility

Aneuploidy

Eligibility Criteria

Sex: All

Age: 21 - 35

Healthy Volunteers: Accepted

Interventions

No clinical intervention is planned; study is observational

Study Details

Brief summary:

To determine the diagnostic accuracy of non-invasive preimplantation genetic testing for aneuploidy (NI-PGT-A) for embryo selection.

Conditions

Infertility

Aneuploidy

Study ID

NCT04732013

Start date

Dec 4, 2020

Status verified date

Apr, 2022

Completion date

Dec 4, 2022

Anticipated

Primary completion date

Sep 4, 2022

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21 - 35

Healthy Volunteers: Accepted

Inclusion Criteria:

Patient undergoing IVF-ICSI at the Olive Fertility Centre

  • 21 - 35 years old at the time of enrolment
  • Elective freeze-all cycle
  • Planning for single embryo transfer

Exclusion Criteria:

  • Undergoing PGT-A, PGT-SR, PGT-M
  • History of recurrent pregnancy loss
  • History of recurrent implantation failure
  • Planning on transfer of more than 1 embryo

Study Design

Enrollment

120 participants

Anticipated

Interventions and Outcome Measures

Arms

Study cohort

Single observational cohort of patients who meet study criteria

Interventions

No clinical intervention is planned; study is observational

No intervention

Primary outcome measure

  • Predictive value of NI-PGT-A results with implantation rate. [ Time Frame: 1 year ]
  • Predictive value of NI-PGT-A results with on-going pregnancy rate. [ Time Frame: 1 year ]
  • Predictive value of NI-PGT-A results with miscarriage rate. [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Gary Nakhuda, MD

604-816-5534nicesttrial@olivefertility.com

Locations

Olive Fertility Centre

Recruiting

Vancouver, British Columbia, Canada, V6R1L4

Contacts

Gary Nakhuda, MD

6048165534nicesttrial@olivefertility.com

Principal Investigator:

Gary Nakhuda, MD

More Information

Sponsor

Olive Fertility Centre

Last update posted

Apr 21, 2022

Last verified

Apr, 2022

Keywords

  • IVF
  • PGT-A
  • Aneuploidy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Olive Fertility Centre on 2022-04-21.