Recruiting

Face Recollection Training

Sponsor:

Boston VA Research Institute, Inc.

Code:

NCT04799340

Conditions

Developmental Prosopagnosia

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Interventions

cognitive training

Study Details

Brief summary:

This study will examine the effectiveness of a cognitive training intervention targeting face recollection, repetition lag training, at improving face recognition in Developmental Prosopagnosia.

Conditions

Developmental Prosopagnosia

Study ID

NCT04799340

Start date

Mar 12, 2021

Status verified date

Nov, 2022

Completion date

Jul 1, 2025

Anticipated

Primary completion date

May 31, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

Developmental prosopagnosic participants will be included if they are...

  • aged 18-90,
  • have lifelong histories of face recognition difficulties that impact their everyday life (i.e., not associated with some event such as a stroke, seizure, etc)
  • score significantly below the mean on the famous faces test and Cambridge Face Memory Test

Exclusion Criteria:

Participants will be excluded from the study if they...

  • have a history of a significant neurological disorder including hydrocephalus, stroke, moderate to severe traumatic brain injury (TBI), severe neuromuscular diseases, or severe hypoxia due to cardiac arrest.
  • have impairments that interfere with cognitive performance, such as uncorrected hearing or vision, lack of English proficiency, musculoskeletal or other issues
  • have psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, chronic intractable obsessive-compulsive disorder, or agoraphobia.
  • We will exclude individuals who are currently dependent on alcohol or other substances, as this may negatively impact cognitive performance.
  • We will exclude participants who currently are, or within the last 6 months, participating in a behavioral or pharmacological intervention.
  • Patients with a history of mild TBI or simple concussion will not be excluded as long as it was > 6 months ago and as long as they have not had repeated concussions (>5)
  • We will include individuals with a diagnosis of ADHD as long as their medication has been consistent for the past 6 months.

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: holistic face training + repetition lag training

no intervention: waitlist control

Interventions

cognitive training

training to improve encoding and recognition of faces

Primary outcome measure

  • Cambridge Face Memory Test [ Time Frame: 15 minutes ]
  • Face Recollection [ Time Frame: 15 minutes ]
  • Face Perception [ Time Frame: 30 minutes ]

Central Contacts and Locations

Central contacts

Joseph M DeGutis, Ph.D.

510-734-7705degutis@hms.harvard.edu

Locations

VA Boston Healthcare System, 150 S. Huntington Ave.

Recruiting

Boston, Massachusetts, United States, 02130

Contacts

Joseph M DeGutis, Ph.D.

510-734-7705degutis@hms.harvard.edu

More Information

Sponsor

Boston VA Research Institute, Inc.

Last update posted

Nov 29, 2022

Last verified

Nov, 2022

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Boston VA Research Institute, Inc. on 2022-11-29.