Recruiting

Relapse Prevention

Sponsor:

New York State Psychiatric Institute

Code:

NCT04810624

Conditions

Anorexia Nervosa

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Not accepted

Interventions

Relapse Prevention and Changing Habits (REACH+)

Study Details

Brief summary:

This study aims to optimize a treatment package for the relapse prevention treatment of AN. In the Preparation Phase, we examined accessibility and feasibility of the treatment package.

In the current Optimization Phase, we will identify which components of treatment contribute to positive outcomes after acute hospitalization. We will carefully evaluate maintenance of remission, measured by rate of weight loss and end-of-trial status.

Conditions

Anorexia Nervosa

Study ID

NCT04810624

Start date

Jun 21, 2021

Status verified date

Mar, 2026

Completion date

Jun 1, 2027

Anticipated

Primary completion date

Jun 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Diagnosis of Anorexia Nervosa at hospital admission
  • Medically Stable
  • Internet capability with videoconferencing
  • Weight restored (BMI > 19 kg/m2) at New York State Psychiatric Institute

Exclusion Criteria:

  • Current substance use or other comorbid disorder requiring specialized treatment
  • Pregnancy
  • Imminent risk of suicide
  • Serious medical illness
  • Daily psychotropic medication other than antidepressants (medications that are known effect weight are exclusionary, i.e. stimulants, olanzapine, mirtazapine)
  • Participation in outside psychotherapy or structured treatment program (support groups will be allowed). Individuals who are discharged on medications would need to have a non-study psychiatrist.

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Factorial

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Do, Accept, Motivation Through Values, Sessions, Long-Term Food Logs,

Behavior Do: Including in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

Food Monitoring - Long-Term: Use of food logs for duration of treatment.

experimental: Do, Accept, Motivation through Values, Sessions, Short-Term Food Logs

Behavior Do: Including in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

Food-Monitoring - Short-Term: Use of food logs for first 5 weeks of treatment.

experimental: Do, Accept, Motivation through Values, Check-Ins, Short-Term Food Logs

Behavior Do: Including in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

Food-Monitoring - Short-Term: Use of food logs for first 5 weeks of treatment.

experimental: Do, Accept, Motivation through Values, Check-Ins, No Food Logs

Behavior Do: Including in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

No Food-Monitoring: No recommendation for food records or logs during treatment.

experimental: Do, Accept, Motivation through Narratives, Sessions, Short-Term Food Logs

Behavior Do: Including in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

Food-Monitoring - Short-Term: Use of food logs for first 5 weeks of treatment.

experimental: Do, Accept, Motivation through Narratives, Sessions, No Food Logs

Behavior Do: Including in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

No Food-Monitoring: No recommendation for food records or logs during treatment.

experimental: Do, Accept, Motivation through Narratives, Check-Ins, Long-Term Food Logs

Behavior Do: Including in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

Food Monitoring - Long-Term: Use of food logs for duration of treatment.

experimental: Do, Change, Motivation Through Values, Sessions, Short-Term Food Logs

Behavior Do: Including in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

Food-Monitoring - Short-Term: Use of food logs for first 5 weeks of treatment.

experimental: Do, Change, Motivation Through Values, Sessions, No Food Logs

Behavior Do: Including in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

No Food-Monitoring: No recommendation for food records or logs during treatment.

experimental: Do, Change, Motivation through Values, Check-Ins, Long-Term Food Logs

Behavior Do: Including in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

Food Monitoring - Long-Term: Use of food logs for duration of treatment.

experimental: Do, Change, Motivation Through Narratives, Sessions, Long-term Food Logs

Behavior Do: Including in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

Food Monitoring - Long-Term: Use of food logs for duration of treatment.

experimental: Talk, Accept, Motivation through Values, Sessions, Short-Term Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

Food-Monitoring - Short-Term: Use of food logs for first 5 weeks of treatment.

experimental: Talk, Accept, Motivation through Values, Sessions, No Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

No Food-Monitoring: No recommendation for food records or logs during treatment.

experimental: Talk, Accept, Motivation through Narratives, Check-Ins, Short-Term Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

Food-Monitoring - Short-Term: Use of food logs for first 5 weeks of treatment.

experimental: Talk, Accept, Motivation through Narratives, Check-Ins, No Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

No Food-Monitoring: No recommendation for food records or logs during treatment.

experimental: Talk, Change, Motivation Through Values, Sessions, Long-Term Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

Food Monitoring - Long-Term: Use of food logs for duration of treatment.

experimental: Talk, Change, Motivation Through Values, Sessions, No Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

No Food-Monitoring: No recommendation for food records or logs during treatment.

experimental: Talk, Change, Motivation through Values, Check-Ins, Short-Term Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

Food-Monitoring - Short-Term: Use of food logs for first 5 weeks of treatment.

experimental: Talk, Change, Motivation through Values, Check-Ins, No Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

No Food-Monitoring: No recommendation for food records or logs during treatment.

experimental: Talk, Change, Motivation through Narratives, Sessions, Short-Term Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

Food-Monitoring - Short-Term: Use of food logs for first 5 weeks of treatment.

experimental: Talk, Change, Motivation through Narratives, Sessions, No Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

No Food-Monitoring: No recommendation for food records or logs during treatment.

experimental: Talk, Change, Motivation through Narratives, Check-Ins, Long-Term Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

Food Monitoring - Long-Term: Use of food logs for duration of treatment.

experimental: Do, Change, Motivation through Narratives, Check-Ins, Short-Term Food Logs

Behavior Do: Including in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

Food-Monitoring - Short-Term: Use of food logs for first 5 weeks of treatment.

experimental: Do, Change, Motivation through Narratives, Check-Ins, No Food Logs

Behavior Do: Including in-session eating experiments.

Thought Change: Monitoring and actively challenging distorted thoughts.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

No Food-Monitoring: No recommendation for food records or logs during treatment.

experimental: Talk, Accept, Motivation through Values, Check-Ins, Long-Term Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Values: Identifying individual motivators for recovery and opportunities to expand upon non-eating disorder aspects of identity.

Check-Ins for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress conducted independently by participant, with only brief (\~20-min) check-ins during this period.

Food Monitoring - Long-Term: Use of food logs for duration of treatment.

experimental: Talk, Accept, Motivation through Narratives, Sessions, Long-Term Food Logs

Behavior Talk: Discussion of recent eating and plans for upcoming eating; absence of in-session eating experiments.

Thought Accept: Mindfully accepting of unhelpful thoughts as passing mental phenomena that need not guide behavior.

Motivation Through Narratives: Using stories of others with lived experience (e.g., writings, podcasts) to appreciate long-term dangers of AN and the opportunity for symptom resolution with sustained recovery, without discussion of individualized motivators.

Sessions for Skills Consolidation: Consolidation of skills introduced to patient and monitoring of continued progress using 45-min, face-to-face (via video) sessions.

Food Monitoring - Long-Term: Use of food logs for duration of treatment.

Interventions

Relapse Prevention and Changing Habits (REACH+)

Psychotherapy

Primary outcome measure

  • Weight maintenance [ Time Frame: 6-month end of treatment ]

Central Contacts and Locations

Central contacts

Locations

New York State Psychiatric Institute

Recruiting

New York, New York, United States, 10032

Contacts

Principal Investigator:

Joanna Steinglass, MD

More Information

Sponsor

New York State Psychiatric Institute

Last update posted

Jun 1, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by New York State Psychiatric Institute on 2026-06-01.