Recruiting
Phase 1
Phase 2

Cell Recovery

Sponsor:

All Natural Medicine Clinic, LLC

Code:

NCT04846010

Conditions

Sequelae of; Infection

Post Infection Glomerulonephritis

Post-Infectious Peripheral Neuralgia

Post-Infectious Disorder (Disorder)

Post-Infectious Arthritis

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Interventions

PurWet

FurFat

PurApo

PurPhl

PurClo

Study Details

Brief summary:

Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period. The virus can cause this continued infection, or the virus causes immune system function disorder and post-infectious autoimmune disease. The clinical symptoms can be smell loss, taste loss to liver function disorder, kidney function failure, different. No matter how complicated the systems showed in the clinic, all of the symptoms are due to the specific cells being damaged. Our clinical study is focused on recovering the damaged structure and function of the cells that could restore the organ function back to normal or close to normal

Conditions

Sequelae of; Infection

Post Infection Glomerulonephritis

Post-Infectious Peripheral Neuralgia

Post-Infectious Disorder (Disorder)

Post-Infectious Arthritis

Study ID

NCT04846010

Start date

Mar 1, 2021

Status verified date

May, 2021

Completion date

Oct 1, 2022

Anticipated

Primary completion date

May 1, 2022

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • The participants must receive medical herbs as a treatment method;
  • Participants are not limited by age, sex, race, or location;
  • Participants are including infants;
  • Participants are including pregnant woman;
  • The participants had an infection history of SARS-CoV-2 in past one month;
  • The participants provide SARS-CoV-s diagnoses (Molecular or Antigen). Test was \*positive, now hold negative reports
  • Participants hold reports of immune system medics, like immunoglobulin M (IgM), immunoglobulin G (IgG);
  • Reports that is evidence of specific organ damaged, including assay reports or image reports
  • Participants must agree to take medical herbs for at least 3 months as one course continually;
  • Participants must agree to repeat the assay and image test to monitor the treatment results;
  • Participants must report their Manifestations clearly to investigators;
  • Participants must agree to continue the next course of the treatment after the evaluation if it is necessary;
  • The treatment goal is to become symptom-free, and experiment assays went to normal

Exclusion Criteria:

  • Participants don't want to take medical herbs;
  • Participants have symptoms of sequelae but is not caused by SARS-CoV-2 (COVID-19);
  • Participants have not symptoms after COVID-19 infection, no assays abnormal either;
  • Participants don't want to repeat the experiment assays;
  • Participants are in E.R. or ICU during the application or enrollment;

Study Design

Enrollment

2000 participants

Anticipated

Allocation

Non randomized

Intervention Model

Sequential

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: antigen

The antigen is the cell that is destroyed by inflammation, which can perform as swollen, fatty, apoptosis, necrosis, and lethal pathological states. Some pathological cells can be saved and returned to customary conditions, like swollen, fatty, early apoptosis, but necrosis, lethal.

active comparator: Internal environment

The internal environment is critical to the damaged cells recovering. Mainly it is covered by two major parts: metabolites and thrombus.

active comparator: Communication between cells

The communication between organs, cells, helps the damaged cells recover and reduce symptoms.

Interventions

PurWet

(1) cang zhu (Atractylodis Rhizoma), bai (zhu Atractylodis macrocephalae Rhizoma), dang shen (Codonopsis Radix), huang qi (Astragali Radix), Fu ling (Poria), Zhu ling (polyporus), Ze xie (Alismatis Rhizoma), Yi yi ren (Coicis Semen), gan cao (Glycyrrhizae Radix),

FurFat

(2).shan zha (Crataegi Fructus), Jue Ming Zi (Cassiae Semen), He ye (Nelumbinis Folium), Da huang (Rhei Radix et Rhizoma), Ze xie (Alismatis Rhizoma), dan shen ( Salviae miltiorrhizae Radix).

PurApo

(3)Sheng Di Huang (Rehmanniae Radix), Xuan Shen (Scrophulariae Radix), mai men dong (Ophiopogonis Radix), shan zhu yu (Corni Fructus), shan yao (Dioscoreae Rhizoma), sha yuan zi (Astragali complanati Semen), ci ji li (Tribuli Fructus), nu zhen zi (Ligustri lucidi Fructus)

PurPhl

(4) chen pi (Citri reticulatae Pericarpium), hua ju hong (Citri grandis Exocartium rubrum), zhi shi (Aurantii Fructus immaturu), zhi ban xia (Pinelliae Rhizoma preparatum), zhi tian nan xing (Arisaematis Rhizoma preparatum),sha ren (Amoni Fructus), Gua lou (Trichosanthis Fructus), Chuan bei mu ( Fritillatiae cirrhosae Bulbu), Fu ling ( Poria), Da huang ( Rhei Radix et Rhizoma).

PurClo

(2) Dan shen (Salviae miltiorrhizae Radix), Yu jin (Curcumae Radix), chi shao (Paeoniae Radix rubra), tao ren (Persicae Semen), hong hua (Carthami Flos)

PurInf

(1) lei gong teng (Tripterygii wilfordii Radix), Huang Qin (Scutellariae Radix), Huang Lian (Coptidis Rhizoma), Huang Bai (Phellodendri Cortex), Zhi Zi (Gardeniae Fructus).

Smoliv

(2). Vagus never communicates with LES: yu jin (Curcumae Radix), Chai Hu (Bupleuri Radix), chi shao (Paeoniae Radix rubra), Mu Dan Pi (Moutan Cortex), chuan lian zi (Toosendan Fructus), long gu (Fossilia Ossis Mastodi), mu li (Ostreae Concha)

Primary outcome measure

  • Monitoring symptoms [ Time Frame: 3 months as a course ]

Central Contacts and Locations

Central contacts

Wanzhu Hou, CMD

(301)770-4480info@anmedicine.com

Locations

All Natural Medicine Clinic, LLC

Recruiting

Rockville, Maryland, United States, 20852-2235

Contacts

Adaobi Mgbodille

301-770-4480info@anmedicine.com

More Information

Sponsor

All Natural Medicine Clinic, LLC

Last update posted

May 26, 2021

Last verified

May, 2021

Keywords

  • treatment of Covid-19 virus infection
  • COVID stress syndrome
  • COVID19 stress syndrome
  • sequelae
  • sequels
  • loss of smell
  • loss of taste
  • emotion disorder
  • panic disorder
  • Post-Traumatic Stress Disorder (PTSD)
  • Depression
  • Anxiety
  • Heartburn
  • GERD
  • Gastroesophageal reflux disease
  • Sleep Disorders

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by All Natural Medicine Clinic, LLC on 2021-05-26.