Recruiting

GLA:D Program

Sponsor:

Marshall University

Code:

NCT04857879

Conditions

Osteoarthritis, Knee

Eligibility Criteria

Sex: All

Age: 45 - 70+

Healthy Volunteers: Not accepted

Interventions

GLA:D program (Good Life with osteoArthritis in Denmark)

Study Details

Brief summary:

This study will examine feasibility of implementing Good Life with Osteoarthritis in Denmark (GLA:D) program in West Virginians with osteoarthritis of the knee

Conditions

Osteoarthritis, Knee

Study ID

NCT04857879

Start date

Aug 6, 2021

Status verified date

Aug, 2021

Completion date

Jul, 2022

Anticipated

Primary completion date

Jun, 2022

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 45 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Between 45 to 90 years of age,
2. Osteoarthritis of the knee (KOA) (Kellgren and Lawrence grade 2, 3, or 4) confirmed by an orthopedic surgeon based on plain film radiographs and symptoms, and
3. Recommendation by an orthopedic surgeon to pursue conservative management of KOA.

Exclusion Criteria:

1. Prior joint replacement surgery in the ipsilateral knee,
2. Known history of cognitive impairments or any neurodegenerative disease,
3. Any other neurological or musculoskeletal pathologies that have resulted in permanent mobility deficits or functional impairments,
4. Medical conditions that would preclude them from participating in exercise programs, and
5. Inability to read and comprehend English.

Study Design

Enrollment

24 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Good Life with Osteoarthritis (GLA:D) Program

Participants will attend 2 sessions aimed at providing disease-specific education followed by 12 sessions of neuromuscular exercises, each 1 hour in length, delivered twice a week over 6 weeks.

active comparator: Control intervention group

Participants allocated to the control intervention will receive disease-specific education and training to learn home exercises in a 1-hour group session. They will receive a booster session 4-weeks after the first session.

Interventions

GLA:D program (Good Life with osteoArthritis in Denmark)

GLA:D includes disease-specific education combined with neuromuscular exercises. Control interventions include disease-specific education combined with exercises to optimize movement and strength of the affected knee.

Primary outcome measure

  • Change in Knee injury and Osteoarthritis Outcome Score (KOOS4) scores from baseline to 12-weeks later [ Time Frame: 12-weeks ]

Central Contacts and Locations

Central contacts

Saurabh P Mehta

3046965620mehtas@marshall.edu

Locations

School of Physical Therapy, Marshall University

Recruiting

Huntington, West Virginia, United States, 25705

More Information

Sponsor

Marshall University

Last update posted

Sep 5, 2021

Last verified

Aug, 2021

Keywords

  • knee arthritis
  • Good Life with Osteoarthritis in Denmark
  • neuromuscular exercises

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Marshall University on 2021-09-05.