Recruiting

Brain-Physical OptimizationBrain-Physical Optimization Conditioning

Sponsor:

Walter Reed Army Institute of Research (WRAIR)

Code:

NCT04863469

Conditions

Physical Performance

Eligibility Criteria

Sex: All

Age: 18 - 40

Healthy Volunteers: Accepted

Interventions

B-POC high load intervention

B-POC low load intervention

Study Details

Brief summary:

Brain-Physical Optimization Conditioning (B-POC) aims to enhance physical performance by expanding the traditional focus of endurance training from purely physical training to the domain of cognitive endurance (Staiano et al., 2015; Dallaway et al., 2017). The current study seeks to isolate neurocognitive mechanisms of performance, particularly under high stress (e.g., physical or cognitive load) conditions, and to develop corresponding cognitive optimization tools.

Conditions

Physical Performance

Study ID

NCT04863469

Start date

Oct 20, 2020

Status verified date

Mar, 2022

Completion date

Oct 20, 2025

Anticipated

Primary completion date

Oct 20, 2023

Anticipated

Eligibility Criteria

Sex: All

Age: 18 - 40

Healthy Volunteers: Accepted

Inclusion Criteria:

Healthy active duty Soldiers
18-40 years old
Available for study duration

Exclusion Criteria:

Failure of an Army Physical Fitness/Combat Test (APFT/ACFT) test
On a physical profile that prevents them from 1) engaging in intense aerobic exercise, 2) running on a treadmill, 3) riding the stationary bike, and 4) performing a cognitive task on a computer screen.
Medically non-deployable
Impaired cognitive function due to medication, injury or illness,
Have been advised by a medical professional not to engage in aerobic exercise
Are a pregnant female

Study Design

Enrollment

66 participants

Anticipated

Allocation

Randomized

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: B-POC high load Intervention

aerobic exercise \[heartrate range (HRR) 70-75% of max HR, on treadmill\] and a computerized high-load task for 45 minutes, 3 times per week, for 6 weeks

sham comparator: B-POC low load intervention

aerobic exercise \[heartrate range (HRR) 70-75% of max HR, on treadmill\] and a computerized low-load task for 45 minutes, 3 times per week, for 6 weeks

Interventions

B-POC high load intervention

aerobic exercise \[heartrate range (HRR) 70-75% of max HR, on treadmill\] and a computerized high-load task for 45 minutes, 3 times per week, for 6 weeks

B-POC low load intervention

aerobic exercise \[heartrate range (HRR) 70-75% of max HR, on treadmill\] and a computerized low-load task for 45 minutes, 3 times per week, for 6 weeks

Primary outcome measure

Time to Failure Test [ Time Frame: 7 weeks ]

Central Contacts and Locations

Central contacts

Brad Fawver, PhD

253-968-4878 bradley.j.fawver.civ@mail.mil

Locations

Medical Research Directorate - West

Recruiting

Tacoma, Washington, United States, 98433

Contacts

Michael M Dretsch

michael.n.dretsch.mil@mail.mil

More Information

Sponsor

Walter Reed Army Institute of Research (WRAIR)

Last update posted

Mar 31, 2022

Last verified

Mar, 2022

Keywords

cognitive fatigue
demand
endurance performance
perceived exertion
effort

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Walter Reed Army Institute of Research (WRAIR) on 2022-03-31.