Recruiting

Observational Study

Sponsor:

CHU de Quebec-Universite Laval

Code:

NCT04889794

Conditions

Major Neurocognitive Disorder

Eligibility Criteria

Sex: All

Age: 65+

Healthy Volunteers: Not accepted

Interventions

GPS clinical intervention

Study Details

Brief summary:

The model of care tested in the GPS project aims to optimize pharmacotherapy for seniors undergoing cognitive assessment or suffering from major neurocognitive disorder (MCND) at home. The goal is to reduce polymedication, inappropriate medications and the treatment burden of seniors and to maintain their cognitive health, quality of life and autonomy. The intervention will include knowledge exchange sessions with nurses, pharmacists, and doctors in FMGs, and increased collaboration between these professionals and home care services teams. Other goal is to increase the satisfaction of the seniors, their families, and the professionals involved in the GPS project.

Conditions

Major Neurocognitive Disorder

Study ID

NCT04889794

Start date

Sep 27, 2021

Status verified date

Aug, 2024

Completion date

Dec, 2026

Anticipated

Primary completion date

Jul, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 65+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • All seniors (65 years of age or older) undergoing cognitive evaluation OR referred to a memory clinic OR having been diagnosed with cognitive impairment within the last year OR with MCND and followed up at home AND,
  • referred to the pharmacist, for the FMGs exposed
  • taking prescription medications

Exclusion Criteria:

  • Seniors in palliative care OR
  • unable to answer questionnaires in French AND without a caregiver.

Study Design

Enrollment

400 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Exposed FMGs to GPS intervention

Patients who are followed by FMGs exposed to the GPS intervention. They will receive the GPS intervention.

no intervention: Non exposed FMGs to GPS intervention

Patients who are part of the FMGs not exposed to the GPS intervention. They will receive the usual care and services.

Interventions

GPS clinical intervention

Nurses and doctors in exposed FMGs and home care teams (HCTs) will be asked to refer to the FMG pharmacist all seniors undergoing cognitive evaluation OR referred to a memory clinic OR recently diagnosed with a cognitive disorder, for a complete and critical review of their medication therapy. FMG pharmacists will be asked to conduct an interview with each referred senior and his or her caregiver, if applicable, in order to establish the best possible treatment regimen. They will compare the information collected with another reliable data source (e.g., pharmacy records) in order to perform medication reconciliation and will then evaluate the medication related problems. Pharmacist will establish a care plan and the follow-ups to be carried out with the patient in collaboration with the health care team. There will be no drug or devices tested, it is a human clinical intervention by a pharmacist.

Primary outcome measure

  • Change in number of prescribed medications [ Time Frame: Baseline, 3 months and 6 months after inclusion in the study. ]

Central Contacts and Locations

Locations

GMF Bordeaux-Cartierville

Recruiting

Montréal, Quebec, Canada, H3M 2X6

Contacts

GMF Abénakis

Recruiting

Saint-Georges, Quebec, Canada, G5Y 5L6

Contacts

More Information

Sponsor

CHU de Quebec-Universite Laval

Last update posted

Aug 22, 2024

Last verified

Aug, 2024

Keywords

  • living lab
  • major neurocognitive disorder
  • polypharmacy
  • health outcomes
  • pharmacists
  • home care
  • family medicine groups
  • deprescribing

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by CHU de Quebec-Universite Laval on 2024-08-22.