Recruiting

Observational Study

Sponsor:

Prisma Health-Upstate

Code:

NCT04947098

Conditions

Cancer

High-Risk Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

Prevent Cancer-Greenville was created to provide individuals with the opportunity to have their risk of developing cancer studied. Some individuals may be at a higher risk due to their personal lifestyle, family history and/or exposures. If subjects are found to be at high risk for developing a disease, they will be sent to a healthcare provider for further care.

Conditions

Cancer

High-Risk Cancer

Study ID

NCT04947098

Start date

Nov 8, 2018

Status verified date

Feb, 2026

Completion date

Nov 8, 2029

Anticipated

Primary completion date

Nov 8, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 18 years or older

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Assess changes in nutrition by nutrition questionnaire [ Time Frame: Yearly follow up for 10 years ]
  • Assess changes in physical activity by physical activity questionnaire [ Time Frame: Yearly follow up for 10 years ]
  • Assess changes in smoking habits [ Time Frame: Yearly follow up for 10 years ]
  • Assess changes in alcohol use [ Time Frame: Yearly follow up for 10 years ]
  • Assess hereditary risk through family history review [ Time Frame: Yearly follow up for 10 years ]
  • Assess lifetime breast cancer risk through the Tyrer-Cuzick version 8 breast risk evaluation tool [ Time Frame: Yearly follow up for 10 years ]
  • Assess 5- year breast cancer risk through the GAIL breast risk evaluation tool [ Time Frame: Yearly follow up for 10 years ]
  • Early detection of malignancies through screening [ Time Frame: Yearly follow up for 10 years ]
  • Assess changes in fat mass by SOZO measurements [ Time Frame: Yearly follow up for 10 years ]
  • Assess changes in muscle mass by SOZO measurements [ Time Frame: Yearly follow up for 10 years ]

Central Contacts and Locations

Central contacts

Patricia Wilson, MSN Ed. OCN ONNCG

864-455-4897ccpw@prismahealth.org

Locations

Prisma Health-Upstate

Recruiting

Greenville, South Carolina, United States, 29605

Contacts

Patricia Wilson, MSN Ed. OCN ONNCG

864-455-4897CCPW@prismahealth.org

Principal Investigator:

Joe Stephenson, MD

More Information

Sponsor

Prisma Health-Upstate

Last update posted

Feb 17, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Prisma Health-Upstate on 2026-02-17.