Recruiting

Observational Study

Sponsor:

Centre hospitalier de l'Université de Montréal (CHUM)

Code:

NCT04973397

Conditions

Preoperative Care

Surgery--Complications

Myocardial Infarction

Eligibility Criteria

Sex: All

Age: 45+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The proportion of noncardiac surgeries performed as same-day surgery is increasing worldwide, with more complex surgeries being performed on higher risk patients in the outpatient setting. Little is known on the risk factors, incidence and prognosis of patients undergoing same-day noncardiac surgery. The main objective of this study is to inform on the incidence and risk factors of cardiovascular and other adverse events after same-day surgery and to develop risk prediction tools to better inform on the risk and selection of patients undergoing same-day surgery.

Conditions

Preoperative Care

Surgery--Complications

Myocardial Infarction

Study ID

NCT04973397

Start date

Nov 17, 2021

Status verified date

Mar, 2026

Completion date

Apr, 2027

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 45+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • 45-64 years of age with at least one risk factor, or ≥65 years of age;
  • undergoing elective noncardiac same-day surgery;
  • planned duration in the operating room 60 minutes or more;
  • provided written consent.

Exclusion Criteria:

  • intervention does not require the presence of an anesthesiologist;
  • procedure is performed by a nonsurgical specialty (e.g., gastroenterology, pneumology, radio-oncology or radiology);
  • intervention is an ophthalmologic procedure;
  • previously enrolled in the VALIANCE study.

Study Design

Enrollment

15000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Unplanned healthcare utilization [ Time Frame: 90 days ]

Central Contacts and Locations

Central contacts

Melodie Fanay Boko, MSc

514-890-8000melodie.fanay.boko.chum@ssss.gouv.qc.ca

Locations

Wake Forest Baptist Medical Centre

Recruiting

Winston-Salem, North Carolina, United States, 27157

Cleveland Clinic Foundation Fairview Campus

Recruiting

Cleveland, Ohio, United States, 44111

Cleveland Clinic Foundation Main Campus

Recruiting

Cleveland, Ohio, United States, 44195

MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Memorial Hermann Texas Medical Center UT Health

Recruiting

Houston, Texas, United States, 77030

Hamilton General Hospital

Recruiting

Hamilton, Ontario, Canada

Juravinski Hospital and Cancer Centre

Recruiting

Hamilton, Ontario, Canada

McMaster University Medical Centre

Recruiting

Hamilton, Ontario, Canada

Mount Sinai Hospital

Recruiting

Toronto, Ontario, Canada, M5G 1X5

Toronto Western Hospital

Recruiting

Toronto, Ontario, Canada, M5T 2S8

St-Micheal's Hospital

Recruiting

Toronto, Ontario, Canada

Centre Hospitalier de l'Université de Montréal (CHUM)

Recruiting

Montreal, Quebec, Canada, H2X0C1

Contacts

Melodie Fanay Boko, BSc

514-890-8000melodie.fanay.boko.chum@ssss.gouv.qc.ca

Principal Investigator:

Emmanuelle Duceppe, MD, PhD

More Information

Sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Last update posted

Mar 19, 2026

Last verified

Mar, 2026

Keywords

  • Preoperative Care
  • Surgery
  • Postoperative complications
  • Same-day surgery
  • Ambulatory surgery
  • Outpatient surgery

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Centre hospitalier de l'Université de Montréal (CHUM) on 2026-03-19.