Recruiting
Phase 2

Observational Study

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT04984551

Conditions

Advanced Malignant Solid Neoplasm

Hematopoietic and Lymphoid Cell Neoplasm

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Interventions

Extension of Community Health (ECHO) Telementoring Clinic

In-Country Workshops

Professional Oncology Educations Programs

Medical Chart Review

Questionnaire Administration

Study Details

Brief summary:

This trial investigates the experience and satisfaction of care in patients with cancer that has spread to other places in the body (advanced) and their caregivers living in underserved areas of Kenya, Nigeria, Ghana, South Africa, India and Ethiopia as part of Project Extension for Community Healthcare Outcomes (ECHO). Project ECHO is a model of medical education and care management that empowers clinicians to provide better care to more people where they live. Understanding the experiences and satisfaction of patients and caregivers may help improve healthcare workforce capacity and increase access to specialty care for the world's rural and underserved populations.

Conditions

Advanced Malignant Solid Neoplasm

Hematopoietic and Lymphoid Cell Neoplasm

Study ID

NCT04984551

Start date

Aug 24, 2020

Status verified date

Mar, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • PATIENT: Scheduled to receive treatment at participating primary care practice for advanced cancer
  • PATIENT: 18 years or older
  • PATIENT: Willing to be accessible to the research team for follow-up by telephone or in person
  • PATIENT: Prognosis of at least 1 year as ascertained by the treating physician
  • PATIENT: Able to read and understand English as assessed by the treating physician
  • CAREGIVER: Identified or self-identified as primary caregiver of the patient
  • CAREGIVER: Willing to be accessible to the research team for follow-up by telephone or in person
  • CAREGIVER: 18 years or older
  • CAREGIVER: Able to read and understand English as assessed by the treating physician
  • ECHO PARTICIPANT: Participant must be a health care provider interested to participate in the study for 2 years and understand the protocol and provide consent
  • ECHO PARTICIPANT: Able to read and understand English as assessed by principal investigator (PI)

Exclusion Criteria:

  • Unable to understand and sign consent

Study Design

Enrollment

312 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Arm I: ECHO Participants (ECHO clinics, workshop, education)

Participants participate in online ECHO clinics over 1 hour twice monthly for 12 months and in-country workshops twice per year. Participants also receive 5 core lectures through an internet-based professional education curriculum.

experimental: Arm II: Patients (questionnaire, medical chart review)

Patients complete 3 in-person or phone questionnaires over a total of 20 minutes every 3 months for 2 years about their symptoms, emotional and physical well-being, and their experience and satisfaction with outpatient oncology care. Patients' medical charts are reviewed for data collection. Patients complete a 15 minute interview in person or phone about the care they received by their physician at baseline, end of month 4 and month 12.

experimental: Arm III: Caregivers (questionnaire)

Caregivers complete an in-person or phone questionnaire over 5 minutes up to 8 times about their experience and satisfaction with the cancer care their family member has received. Caregivers complete a 15-minute interview in person or by phone their family member received by their physician.

Interventions

Extension of Community Health (ECHO) Telementoring Clinic

Participate in ECHO clinics presenting cases for guidance and feedback

In-Country Workshops

In-Country Workshops Participate in hands-on training and workshops

Professional Oncology Educations Programs

Receive 5 core online lectures

Medical Chart Review

Medical charts are reviewed for data collection

Questionnaire Administration

Complete questionnaire(s)

Primary outcome measure

  • Change in patients' quality of life [ Time Frame: Baseline up to 12 months ]

Central Contacts and Locations

Central contacts

Sriram Yennu

713-792-6085syennu@mdanderson.org

Locations

M D Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Sriram Yennu

713-792-6085

Principal Investigator:

Sriram Yennu

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Mar 5, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-03-05.