Recruiting

Behavioral Weight Loss

Sponsor:

UCLA

Code:

NCT04997473

Conditions

Obesity

Stem Cell Transplant

Eligibility Criteria

Sex: All

Age: 13 - 30

Healthy Volunteers: Accepted

Interventions

W8L2G mobile health (mHealth) app

Study Details

Brief summary:

Pilot study enrolling obese post HSCT (hematopoietic stem cell transplantation) patients at the hematology/oncology clinic at the Mattel Children's Hospital, University of California, Los Angeles. Parameters include percent over the 95th percentile (%BMIp95), zBMI, fasting metabolic metrics, addictive eating habits, and motivation for change.

Conditions

Obesity

Stem Cell Transplant

Study ID

NCT04997473

Start date

Aug 15, 2021

Status verified date

Jan, 2026

Completion date

Jan 9, 2027

Anticipated

Primary completion date

Jan 9, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 13 - 30

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Patients ≥ 13 and ≤ 30 years old with a history of HSCT of any type, at least 100 days post-transplant at initial consultation of the study, will be eligible for the study.
  • Both male and female patients will be eligible.
  • Patients must classify as obese, represented as Body mass index \[BMI\] ≥85th percentile for age and gender.
  • Patients must also be able to read English since the app intervention is only available in English form.

Exclusion Criteria:

  • Patients who are ≤ 13 or ≥ 30 years old are not eligible for the study.
  • Patients who are < 100 days post-transplant at initial consultation will not be eligible for the study, but may become eligible if they are >100 days post-transplant at their next consultation that falls within the enrollment window.
  • Patients whose BMI does not fall under the obese category will be excluded.
  • No patients will be excluded for any specific underlying medical condition, but decisions will be made on a case by case basis if a patient's functioning is deemed to significantly interfere with intervention participation.

Study Design

Enrollment

20 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: App Group

Participants will be receiving an addiction model based mobile health (mHealth) weight loss intervention with coaching for a total of 4 months duration

Interventions

W8L2G mobile health (mHealth) app

Weight loss phone app based on addiction principles. This intervention has been validated in two prior studies. Participants will also interact with coaches throughout the intervention

Primary outcome measure

  • BMI [ Time Frame: 4 months ]

Central Contacts and Locations

Central contacts

Belen Ramirez

3102670425belenramirez@mednet.ucla.edu

Locations

UCLA Mattel Children's Hospital

Recruiting

Los Angeles, California, United States, 90095

Contacts

Belen Ramirez

3102670425belenramirez@mednet.ucla.edu

More Information

Sponsor

University of California, Los Angeles

Last update posted

Jan 28, 2026

Last verified

Jan, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, Los Angeles on 2026-01-28.