Recruiting

Observational Study

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT05046080

Conditions

Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type

Eligibility Criteria

Sex: Female

Age: 0+

Healthy Volunteers: Not accepted

Interventions

Electronic Health Record Review

Laboratory Biomarker Analysis

Study Details

Brief summary:

This study aims to provide a comprehensive report on clinicopathologic features, immunohistochemical/biomarker testing and molecular profile of cervical clear cell carcinoma. This study may help researchers learn more about the molecular profile of cervical clear cell carcinoma.

Conditions

Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type

Study ID

NCT05046080

Start date

Aug 6, 2021

Status verified date

Aug, 2026

Completion date

Sep 29, 2026

Anticipated

Primary completion date

Sep 29, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients diagnosed with clear cell carcinoma of the cervix at MDACC

Study Design

Enrollment

70 participants

Anticipated

Interventions and Outcome Measures

Arms

Observational (medical record review)

Patients' medical records are reviewed retrospectively, and archival tumor tissue analyzed by immunohistochemistry and next generation sequencing.

Interventions

Electronic Health Record Review

Medical records reviewed

Laboratory Biomarker Analysis

Correlative studies

Primary outcome measure

  • Clinicopathologic study on patients diagnosed and treated for clear cell carcinoma of the cervix [ Time Frame: through study completion, an average of 1 year ]

Central Contacts and Locations

Locations

M D Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Anasis Malpica

713-792-4655amalpica@mdanderson.org

Principal Investigator:

Anasis Malpica

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Aug 10, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-08-10.