Recruiting

Point-of-Care Ultrasound

Sponsor:

WellSpan Health

Code:

NCT05050617

Conditions

Pulmonary Embolism

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Point-of-care echocardiography

Study Details

Brief summary:

This study is an observational, prospective study examining the role point-of-care echocardiography of predicting short term adverse outcomes in emergency department patients with acute pulmonary embolism.

The primary objective is to assess the diagnostic performance of ultrasound-guided measures of right ventricular dilation (RVD) and strain in predicting clinical outcomes in acute PE.

The secondary objective is to investigate the utility of combining ultrasound-guided measures of RVD and the pulmonary embolism severity index (PESI) score in predicting adverse outcomes in acute PE.

Conditions

Pulmonary Embolism

Study ID

NCT05050617

Start date

Sep 9, 2021

Status verified date

Jun, 2026

Completion date

Dec, 2026

Anticipated

Primary completion date

Sep, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age >= 18 years of age
  • ED diagnosis of acute pulmonary embolism with identification on CT imaging

Exclusion Criteria:

  • Age <18 years of age
  • Inability to provide informed consent
  • Incarceration
  • Current PE previously diagnosed prior to index ED visit

Study Design

Enrollment

250 participants

Anticipated

Interventions and Outcome Measures

Arms

Acute Pulmonary Embolism

Subjects in this single cohort will undergo point-of-care echocardiography at the time of presentation and subsequent follow up to assess for short term adverse events or complications.

Interventions

Point-of-care echocardiography

Subjects will undergo point-of-care echocardiography at the time of presentation/enrollment to assess for evidence of right sided heart dilation/strain.

Primary outcome measure

  • Adverse Events at 5 days [ Time Frame: Within 5 days of presentation/enrollment ]

Central Contacts and Locations

Central contacts

Brent A Becker, MD

717 851 4819bbecker2@wellspan.org

Kristen Oliff, BS

717 851 4104koliff@wellspan.org

Locations

Wellspan York Hospital

Recruiting

York, Pennsylvania, United States, 17403

Contacts

Brent Becker, MD

717 851 4819bbecker2@wellspan.org

Kristen Oliff, BS

717 851 4104koliff@wellspan.org

More Information

Sponsor

WellSpan Health

Last update posted

Jun 3, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by WellSpan Health on 2026-06-03.