MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

Recruiting

Phase 1

Metformin & Insulin DeliveryMANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

Sponsor:

Kalie Tommerdahl

Code:

NCT05065372

Conditions

Type 1 Diabetes

Diabetic Kidney Disease

Cardiovascular Diseases

Endothelial Dysfunction

Insulin Sensitivity

Eligibility Criteria

Sex: All

Age: 12 - 25

Healthy Volunteers: Not accepted

Interventions

Metformin Hcl 1000Mg Tab

Aminohippurate Sodium 20 % Injection

Iohexol 300 Mg/mL Injectable Solution

Placebo

Study Details

Eligibility Criteria

Study Design

Interventions and Outcome Measures

Central Contacts and Locations

More Information

Trial information was received from ClinicalTrials.gov and was last updated on 2025-12-14. This information was provided to ClinicalTrials.gov by Kalie Tommerdahl on 2025-06-13.