Recruiting

Focused Muscle Contraction Therapy

Sponsor:

University of Illinois at Chicago

Code:

NCT05094297

Conditions

Chronic Pain

Acute Pain

Fatigue

Depression

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Investigate the effects of an exercise intervention on U.S. Veterans.

Study Details

Brief summary:

This research study is being done to investigate if the GH Method exercise program positively affects body composition, improves physical abilities and can improve the overall sense of wellbeing (e.g. depression, PTSD, etc.) in U.S. Veterans. Subjects will be asked to complete 94 total visits (four (4) study testing visits and 90 exercise visits). Enrolled subjects will be tested for fitness, strength, and health risk factors at UIC 4 times and will complete 90 exercise training visits at the GH FITLab over the next 18 months. Subjects will also be asked to complete questionnaires about depression, post-traumatic stress symptoms and thoughts about harming oneself.

Conditions

Chronic Pain

Acute Pain

Fatigue

Depression

Study ID

NCT05094297

Start date

Oct 1, 2021

Status verified date

Sep, 2025

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • U.S. Veterans
  • Eligible subjects must be patients at the Jesse Brown VA Medical Center and suffer from pain, fatigue, low energy levels or are unable to physically do things they were once able to do.
  • Subjects need to complete the PAR-Q with an acceptable score and/or must have written physician clearance.
  • 18 years of age and older

Exclusion Criteria:

  • Unable to travel to the training center
  • Unable to give consent
  • Unable to understand the study
  • Unable to comply with the training program

Study Design

Enrollment

25 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Investigate the effects of an exercise intervention on U.S. Veterans.

A total of 25 U.S. Veterans (≥ 18 years of age), who suffer from pain, fatigue, low energy levels or are unable to physically do things they were once able to do, will be enrolled.

Interventions

Investigate the effects of an exercise intervention on U.S. Veterans.

Enrolled subjects will be asked to complete 94 total visits (4 study testing visits and 90 exercise visits). They will be tested for fitness, strength, and health risk factors at UIC 4 times and will complete 90 exercise training visits at the GH FITLab over the next 18 months.

Primary outcome measure

  • Rate at which exercise will change body composition [ Time Frame: 18 months ]
  • Rate at which exercise will change body composition [ Time Frame: 18 months ]

Central Contacts and Locations

Central contacts

Ilaria Santi

312-996-4706isanti@uic.edu

Natalie Isho, MPH

312-996-4706nisho@uic.edu

Locations

University of Illinois at Chicago

Recruiting

Chicago, Illinois, United States, 60612

Contacts

Natalie Isho, MPH

312-996-4706nisho@uic.edu

Principal Investigator:

Enrico Benedetti, MD

More Information

Sponsor

University of Illinois at Chicago

Last update posted

Sep 19, 2025

Last verified

Sep, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Illinois at Chicago on 2025-09-19.