Recruiting

Attentional Bias Modification

Sponsor:

University of Wisconsin, Milwaukee

Code:

NCT05112562

Conditions

E-cigarette Use

Tobacco Use Cessation

Eligibility Criteria

Sex: All

Age: 18 - 29

Healthy Volunteers: Accepted

Interventions

Computerized attentional bias modification training

Placebo attention control training

Study Details

Brief summary:

Aims are to (1) evaluate attentional bias to e-cigarette cues between the intervention and control groups at post-intervention as compared to the pre-intervention; and (2) test the feasibility and efficacy of the intervention at post-intervention. To accomplish these aims, a theory-driven parallel, controlled 2-arm randomized clinical trial will be conducted with young adult e-cigarette users (approximately N = 50). Outcomes are attentional bias to e-cigarette cues and abstinence outcomes including nicotine dependence, and arousal/urges for e-cigarette use.

Conditions

E-cigarette Use

Tobacco Use Cessation

Study ID

NCT05112562

Start date

Jun 9, 2021

Status verified date

Nov, 2022

Completion date

Dec 31, 2024

Anticipated

Primary completion date

May 31, 2023

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 29

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 18 and 29 years
  • Those who use ENDS exclusively, not combining with other tobacco, for 3 consecutive months
  • Those who own a smartphone.

Exclusion criteria:

  • Current medication or psychosocial treatment for ENDS dependence
  • Serious alcohol-use problems (≥ 26 points on the Alcohol Use Disorders Identification Test)
  • Ophthalmic conditions impeding eye-tracking
  • Current psychiatric/psychosocial treatment for other mental health disorders in the DSM-5 (e.g., schizophrenia)
  • Pregnancy.

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Computerized attentional bias modification training

placebo comparator: Placebo attention control training

Interventions

Computerized attentional bias modification training

In intervention is designed to train participants to disengage attention from potent e-cigarette cues and is based on the well-established attention retraining paradigm for other psychopathologies.

Placebo attention control training

This control training is very similar to the intervention's overall task structure and stimuli. The only difference is that the this control program is designed to exert no systematic manipulation on the attention deployment pattern between the two stimulus categories, thereby yielding no significant impact on the level of attentional bas toward ENDS-related cues

Primary outcome measure

  • Attentional bias to e-cigarette cues measured by cueing task [ Time Frame: Pre-training ]
  • Attentional bias to e-cigarette cues measured by cueing task [ Time Frame: 1-month follow up ]
  • Attentional bias to e-cigarette cues measured by cueing task [ Time Frame: 2-months follow up ]
  • Attentional bias to e-cigarette cues measured by cueing task [ Time Frame: 4-months follow up ]

Central Contacts and Locations

Central contacts

Seok Hyun Gwon, PhD, RN

414-229-6462gwon@uwm.edu

Han Joo Lee, PhD

leehj@uwm.edu

Locations

University of Wisconsin-Milwaukee

Recruiting

Milwaukee, Wisconsin, United States, 53211

Contacts

Seok Hyun Gwon, PhD, RN

414-229-6462gwon@uwm.edu

Han Joo Lee, PhD

leehj@uwm.edu

More Information

Sponsor

University of Wisconsin, Milwaukee

Last update posted

Nov 4, 2022

Last verified

Nov, 2022

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by University of Wisconsin, Milwaukee on 2022-11-04.