Recruiting

Disinfection By-Products

Sponsor:

Anna Hoover

Code:

NCT05172752

Conditions

Disinfection By-products

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Citizen Scientist Training Program

Stakeholder Consultation Core Program

Study Details

Brief summary:

Appalachian Kentuckians in Martin and Letcher Counties are grappling with a health-threatening drinking water crisis arising from exposures to disinfection by-products (DBPs). DBPs include trihalomethanes (THMs), haloacetic acids (HAAs), chlorate, and other compounds that have been associated with a variety of adverse health effects, including increased risk of bladder cancer and cardiovascular birth defects. This study implements a multi-stakeholder, multi-method approach to improve understanding of, characterize spatial and temporal variations in, and reduce exposure to DBPs in these Appalachian Kentucky counties.

Conditions

Disinfection By-products

Study ID

NCT05172752

Start date

Feb 25, 2022

Status verified date

Jul, 2026

Completion date

Oct, 2026

Anticipated

Primary completion date

Oct, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Located in Martin or Letcher County water districts
  • At least 18 years old
  • Able to read/speak in English

Exclusion Criteria:

  • Located outside of Martin or Letcher County water districts

Study Design

Enrollment

200 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

other: Citizen Science Training

Study participants in this condition will participate in training and in-home sampling for disinfection by-products.

other: Stakeholder Consultation Core Membership

Study participants in this condition will participate in quarterly meetings and deliberative activities of the project's Stakeholder Consultation Core.

Interventions

Citizen Scientist Training Program

Citizen Scientist Training Program Participants is a three year training and in-home sampling program for disinfection byproducts. Participants will be trained and assessed based on their experience in the training program.

Stakeholder Consultation Core Program

Stakeholder Consultation Core Program Participants is a five year assessments where participants will participate in quarterly meetings and deliberative activities related to disinfection byproducts. Participants will be assessed based on their experience in the program.

Primary outcome measure

  • Change in Environmental Health Literacy (EHL) - Knowledge [ Time Frame: Baseline, 5-years ]
  • Change in Environmental Health Literacy (EHL) - Attitudes/Behaviors [ Time Frame: Baseline, 5-years ]
  • Change in participant network density [ Time Frame: Baseline, 5-years ]
  • Change in participant centrality [ Time Frame: Baseline, 5-years ]
  • Change in participant reciprocity [ Time Frame: Baseline, 5-years ]

Central Contacts and Locations

Central contacts

Anna Hoover, PhD

859-218-0343Anna.Hoover@uky.edu

Jason Unrine, PhD

859-257-1657jason.unrine@uky.edu

Locations

University of Kentucky

Recruiting

Lexington, Kentucky, United States, 40536

More Information

Sponsor

Anna Hoover

Last update posted

Aug 27, 2026

Last verified

Jul, 2026

Keywords

  • Community-engaged
  • Appalachia

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Anna Hoover on 2026-08-27.