Recruiting

Error-Enhanced Learning

Sponsor:

Shirley Ryan AbilityLab

Code:

NCT05180786

Conditions

Stroke

Cerebral Vascular Accident (CVA)/Stroke

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Error Fields

No Error Fields

Study Details

Brief summary:

This study is being done to see how errors lead to improvement. Specifically, we are evaluating the errors stroke participants make during an upper extremity exercise program when reaching for a target using their affected arm. Once we understand the participant's reaching errors, we plan to create a customized reaching exercise according to the individual's specific error tendencies which will lead to better performance on movement ability after training.

Conditions

Stroke

Cerebral Vascular Accident (CVA)/Stroke

Study ID

NCT05180786

Start date

Mar 1, 2023

Status verified date

Sep, 2024

Completion date

Dec 30, 2025

Anticipated

Primary completion date

Dec 30, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

1. 18 years of age or older
2. Chronic stroke (8+ months post stroke event) with primary motor cortex involvement
3. Hemiparesis
4. Some degree of both shoulder and elbow movement capability

Exclusion Criteria:

1. Bilateral paresis
2. Severe tactile deficits using the Two-Point Discrimination Test (participant must detect<11mm)
3. Severe proprioceptive deficits
4. Severe spasticity (Modified Ashworth >3) preventing movement
5. Aphasia, cognitive impairment, or affective dysfunction that would influence the ability to perform the experiment
6. Visual deficits, and hemispatial neglect that would prevent the subjects from seeing the targets.
7. Inability to provide an informed consent
8. severe current medical problems
9. diffuse/multiple lesion sites or multiple stroke events
10. Inability to attain and maintain testing positions
11. Botox injection to the affected upper extremity within the previous 4 months
12. Concurrent participation in upper extremity rehabilitation either as part of a research intervention protocol or a prescribed therapy
13. Participation in previous, similar robotics intervention study
14. Other neurological issues

None of the following special populations will be included in this research study:

  • Adults unable to consent
  • Individuals who are not yet adults (infants, children, teenagers)
  • Pregnant women
  • Prisoners
  • Vulnerable Populations

Study Design

Enrollment

20 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

other: Group 1

other: Group 2

Interventions

Error Fields

Participants will complete a reaching experiment using the robotic arm with error fields turned on.

No Error Fields

Participants will complete a reaching experiment using the robotic arm with error fields turned off.

Primary outcome measure

  • Perpendicular Error [ Time Frame: 60-90 minutes ]

Central Contacts and Locations

Central contacts

Locations

Shirley Ryan AbilityLab (Healthy Participants)

Recruiting

Chicago, Illinois, United States, 60611

Contacts

Naveed Aghamohammadi

765-421-5544nagham2@uic.edu

Shirley Ryan AbilityLab

Recruiting

Chicago, Illinois, United States, 60611

Contacts

Courtney Celian, MSOT

312-238-1560ccelian@sralab.org

Shirley Ryan AbilityLab

Recruiting

Chicago, Illinois, United States, 60611

Principal Investigator:

James Patton, PhD

More Information

Sponsor

Shirley Ryan AbilityLab

Last update posted

Oct 24, 2024

Last verified

Sep, 2024

Keywords

  • Upper Extremity
  • Rehabilitation
  • Arm
  • Robotics
  • Stroke

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Shirley Ryan AbilityLab on 2024-10-24.