Recruiting

Nitrate Supplementation

Sponsor:

University of Texas at Austin

Code:

NCT05188079

Conditions

Healthy Adults

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Interventions

Beetroot juice

Placebo drink

Study Details

Brief summary:

The purpose of the study is to assess vascular function in African Americans, Hispanic and Caucasian Americans to better understand racial differences in cardiovascular health. The investigators will further investigate the affect of Beetroot juice on the vascular function of all participants.

Conditions

Healthy Adults

Study ID

NCT05188079

Start date

Oct 1, 2021

Status verified date

Jan, 2025

Completion date

Jan 31, 2028

Anticipated

Primary completion date

Aug 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Healthy men and women who are either Caucasian American, Hispanic, or non-Hispanic African American

Exclusion Criteria:

  • Blood pressure higher than or equal to 140/90 mmHg
  • BMI > 35kg/m2
  • Have a history of cardiovascular, neurological or vascular diseases
  • Take prescription medications
  • Are smokers
  • Are pregnant

Study Design

Enrollment

90 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

active comparator: Beetroot Juice

140 ml of beetroot juice (high nitrate dietary supplement)

placebo comparator: Placebo

Placebo drink looks and tastes like the beetroot juice but has the nitrate removed from the juice.

Interventions

Beetroot juice

high nitrate supplement

Placebo drink

placebo

Primary outcome measure

  • Forearm blood flow [ Time Frame: through study completion, an average of 2 year ]

Central Contacts and Locations

Central contacts

jasdeep kaur, PhD

5124718595jasdeep.kaur@austin.utexas.edu

Locations

University of Texas at Austin

Recruiting

Austin, Texas, United States, 78712

Contacts

Jasdeep Kaur, PhD

512-471-8595jasdeep.kaur@austin.utexas.edu

More Information

Sponsor

University of Texas at Austin

Last update posted

Jan 16, 2025

Last verified

Jan, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Texas at Austin on 2025-01-16.