Recruiting

RFA

Sponsor:

Columbia University

Code:

NCT05189314

Conditions

Thyroid Nodules

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Thyroidectomy

Radiofrequency Ablation

Study Details

Brief summary:

The purpose of this observational research is to evaluate and compare clinical outcomes after treatment for symptomatic benign multinodular goiter (MNG) patients. This is a data collection study in which we ask participants to give access to information generated before and after treatment of their condition.

Conditions

Thyroid Nodules

Study ID

NCT05189314

Start date

Aug 30, 2019

Status verified date

May, 2026

Completion date

Aug, 2028

Anticipated

Primary completion date

Aug, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adult patients >/=18 years old with benign thyroid nodules

Exclusion Criteria:

  • cardiac arrhythmia
  • pregnancy

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Arms

Thyroidectomy

Patients with benign thyroid nodules who undergo surgical resection

RFA

Patients with benign thyroid nodules who undergo radiofrequency ablation

Interventions

Thyroidectomy

Surgical Resection of thyroid nodules

Radiofrequency Ablation

Radiofrequency Ablation of thyroid nodules

Primary outcome measure

  • Percent Volume Change of Nodules [ Time Frame: 6 months and 12 months ]
  • Change in Thyroid Stimulating Hormone (TSH) [ Time Frame: 6 months and 12 months ]
  • ThyPRO 39 Survey Score [ Time Frame: 12 months ]

Central Contacts and Locations

Central contacts

Jennifer H Kuo, MD MS

212-305-6969jhk2029@cumc.columbia.edu

Vilma Rosario

vr2222@cumc.columbia.edu

Locations

Columbia University

Recruiting

New York, New York, United States, 10032

Contacts

Jennifer H Kuo, MD MS

212-305-6969jhk2029@cumc.columbia.edu

More Information

Sponsor

Columbia University

Last update posted

May 29, 2026

Last verified

May, 2026

Keywords

  • Radiofrequency Ablation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Columbia University on 2026-05-29.