Recruiting

MRI Software & Hardware

Sponsor:

Northwestern University

Code:

NCT05215132

Conditions

Image, Body

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Interventions

MRI

Gadavist 2Ml Solution for Injection

Study Details

Brief summary:

Patients and healthy volunteers will be scanned in order to test new sequences.

Conditions

Image, Body

Study ID

NCT05215132

Start date

Dec 19, 2019

Status verified date

Apr, 2026

Completion date

Jan 31, 2028

Anticipated

Primary completion date

Jan 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • • At least 18 years of age

  • Able to complete the MR safety questionnaire.
  • Able to comprehend and provide informed consent in English.
  • When contrast is being administered: healthy volunteers with a GFR≥60 ml/min
  • When contrast is being administered: patients with a GFR ≥30 ml/min

Exclusion Criteria:

  • • When contrast is being administered: subjects with a GFR < 30 ml/min

  • When contrast is being administered: subjects with acute kidney injury
  • When contrast is administered, allergy to gadolinium-containing contrast media
  • Contraindication to MRI (implanted device, claustrophobia, dyspnea precluding the ability to follow breath-hold instructions)
  • Adults unable to consent
  • Individuals who are not yet adults
  • Pregnant or breastfeeding women
  • Prisoners

Study Design

Enrollment

2000 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Diagnostic

Interventions and Outcome Measures

Arms

other: Patient w/ Contrast

Patients will add 15 minutes to their SOC MRI for research purposes

other: Patient no contrast

Patients will add 15 minutes to their SOC MRI for research purposes

other: Volunteer w/ contrast

Volunteers undergo 1 research MRI for research purposes

other: Volunteer no contrast

Volunteers undergo 1 research MRI for research purposes

Interventions

MRI

1.5T or 3T MRI scanner (Siemens Medical Systems)

Gadavist 2Ml Solution for Injection

Arm 1 and Arm 3 subjects will undergo this intervention (Gadavist 2Ml solution)

Primary outcome measure

  • Conduct clinical protocol development and validation [ Time Frame: 5 years ]

Central Contacts and Locations

Central contacts

Emily Powell

312.695.2956emily.powell@northwestern.edu

Saira Jahangir

s-jahangir@northwestern.edu

Locations

Northwestern University- Feinberg School of Medicine

Recruiting

Chicago, Illinois, United States, 60611

Contacts

Emily Powell

3126952956emily.powell@northwestern.edu

Saira Jahangir

s-jahangir@northwestern.edu

Principal Investigator:

Ryan Avery

More Information

Sponsor

Northwestern University

Last update posted

Apr 24, 2026

Last verified

Apr, 2026

Keywords

  • MRI hardware testing

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Northwestern University on 2026-04-24.