Recruiting

Observational Study

Sponsor:

Old Dominion University

Code:

NCT05217589

Conditions

Other Gastrointestinal Disorders

Cramp, Abdominal

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Accepted

Interventions

Funny/Amusing Video Clips

Horror/Scary Video Clips

Thrilling/Suspenseful Video Clips

Study Details

Brief summary:

Many athletes anecdotally report modifying their nutritional intake before competition in order to avoid gut problems, but no studies have evaluated whether emotional state impacts tolerance to pre-exercise feeding. Therefore, this study will use movie clips (stressful, horror, and funny/amusing) to induce different mood states and emotions, which will be followed by ingestion of food before endurance running on a treadmill. In addition, metabolic and physiologic responses to mood induction will be evaluated.

Conditions

Other Gastrointestinal Disorders

Cramp, Abdominal

Study ID

NCT05217589

Start date

Apr 1, 2022

Status verified date

Mar, 2025

Completion date

Dec 31, 2025

Anticipated

Primary completion date

Dec 1, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Accepted

Inclusion Criteria:

1. Aged 18 to 55 years
2. Able to run for 30 min at a moderate-to-vigorous intensity without stopping
3. No diagnosis or signs/symptoms of cardiovascular disease (CVD) or metabolic disorders
4. Currently physically active (at least 3 days/week of exercise at a moderate or higher intensity)
5. No visual or hearing impairments interfering with ability to see and hear video clips
6. No allergies to ingredients in Boost drink

Exclusion Criteria:

1. Aged <18 or >55 years
2. Unable to run for 30 min at a moderate-to-vigorous intensity without stopping
3. A diagnosis or signs/symptoms of CVD or metabolic disorders
4. Currently physically inactive (< 3 days/week of exercise at a moderate or higher intensity)
5. Visual or hearing impairments interfering with ability to see and hear video clips
6. Allergies to ingredients in Boost drink

Study Design

Enrollment

90 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Funny/Amusing Video Clips

Participants will watch 5-7-min video clips that are meant to be funny/amusing

experimental: Horror/Scary Video Clips

Participants will watch 5-7-min video clips that are meant to be scary

experimental: Thrilling/Suspenseful Video Clips

Participants will watch 5-7-min video clips that are meant to be thrilling/suspenseful

Interventions

Funny/Amusing Video Clips

Participants watch 5-7 minutes of video clips that are funny/amusing in nature

Horror/Scary Video Clips

Participants watch 5-7 minutes of video clips that are scary in nature

Thrilling/Suspenseful Video Clips

Participants watch 5-7 minutes of video clips that are thrilling/suspenseful in nature

Primary outcome measure

  • Total exercise gastrointestinal symptom burden [ Time Frame: Total GI symptom burden over a 30-minute jogging/running protocol. ]
  • Change in emotion ratings [ Time Frame: Change in emotion ratings between immediately pre-video and immediately post-video. ]

Central Contacts and Locations

Central contacts

Patrick Wilson, PhD

7576834783pbwilson@odu.edu

Locations

Human Performance Laboratory

Recruiting

Norfolk, Virginia, United States, 23529

Contacts

More Information

Sponsor

Old Dominion University

Last update posted

Mar 20, 2025

Last verified

Mar, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-05. This information was provided to ClinicalTrials.gov by Old Dominion University on 2025-03-20.