Trastuzumab & PertuzumabTesting the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Sponsor:

National Cancer Institute (NCI)

Code:

NCT05256225

Conditions

Endometrial Carcinoma

Endometrial Clear Cell Adenocarcinoma

Endometrial Dedifferentiated Carcinoma

Endometrial Endometrioid Adenocarcinoma

Endometrial Mixed Cell Adenocarcinoma

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Carboplatin

Computed Tomography

Echocardiography Test

High-Dose-Rate Vaginal Cuff Brachytherapy

Study Details

Eligibility Criteria

Study Design

Interventions and Outcome Measures

Central Contacts and Locations

More Information

Trial information was received from ClinicalTrials.gov and was last updated on 2026-08-21. This information was provided to ClinicalTrials.gov by National Cancer Institute (NCI) on 2026-08-19.