Recruiting

Observational Study

Sponsor:

Loma Linda University

Code:

NCT05285007

Conditions

Patellofemoral Pain

Eligibility Criteria

Sex: Female

Age: 18 - 59

Healthy Volunteers: Accepted

Interventions

Mobilization with Movement

No mobilization with movement and education

Study Details

Brief summary:

The purpose of this graduate student research study is to investigate the relationship between limited ankle dorsiflexion and the potential effects on a single limb squat task in the Patellofemoral/Knee Pain population.

Conditions

Patellofemoral Pain

Study ID

NCT05285007

Start date

Mar 2, 2022

Status verified date

Aug, 2026

Completion date

May, 2027

Anticipated

Primary completion date

May, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 59

Healthy Volunteers: Accepted

Inclusion Criteria:

  • History of active Patellofemoral Pain for at least 6 months
  • No clinic based therapeutic interventions for a 6-month period prior to testing
  • Females aged 18-59 years' old
  • Limited ankle dorsiflexion as noted by <45degs using the weight bearing lunge test

Exclusion Criteria:

  • History of musculoskeletal surgery or fractures on the tested leg or lumbar spine that could affect their biomechanics during the study
  • History of soft tissue or skeletal abnormalities in the tested limb
  • Current knee effusion
  • Resting pain greater than 5/10

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Primary Intervention Group

The experimental group will receive two interventions to increase dorsiflexion range of motion.

active comparator: Minimal Intervention Group

The minimal intervention group will read and infographic and complete 5 minutes of treadmill walking.

Interventions

Mobilization with Movement

Participants will be lunging on a box with posterior ankle glide of 10 seconds times 5 sets. They will have 30 seconds rest between trials. Participant will have their ankle taped and then walk on a treadmill at a self-selected pace for 5 minutes.

No mobilization with movement and education

Participants ankle will not be taped and they will walk on the treadmill for 5 minutes and receive education.

Primary outcome measure

  • Weight bearing lunge test [ Time Frame: change between baseline and post intervention on Day 1 ]

Central Contacts and Locations

Central contacts

Everett Lohman, DSc

909-558-4632elohman@llu.edu

Locations

Loma Linda University

Recruiting

Loma Linda, California, United States, 92350

Contacts

Everett Lohman, DSc

909-558-4632elohman@llu.edu

More Information

Sponsor

Loma Linda University

Last update posted

Aug 20, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Loma Linda University on 2026-08-20.