Recruiting

Observational Study

Sponsor:

VA Office of Research and Development

Code:

NCT05288803

Conditions

Total Knee Arthroplasty

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Clinical decision support tool (CDS tool)

Study Details

Brief summary:

This study will examine the impact of a new clinical decision support tool for rehabilitation after total knee arthroplasty (TKA). Typically, TKA rehabilitation is generic with most patients receiving the same dosage and contents of rehabilitation despite notable diversity among patients who undergo TKA. The investigators clinical support decision tool is designed to help physical therapists tailor rehabilitation treatments and dosages to the individual needs, goals, and preferences of Veterans recovering from TKA. This study has the potential to improve Veterans' functional recovery after TKA, while simultaneously reducing the average number of physical therapy visits Veterans attend after surgery by tailoring rehabilitation dosage based upon need. This will ensure the Veterans Health Administration (VHA) has the resources and capacity to provide adequate rehabilitation to every Veteran seeking TKA in the VHA system. Additionally, if successful, this clinical decision support tool could be used to improve outcomes and access for additional patient populations in the future.

Conditions

Total Knee Arthroplasty

Study ID

NCT05288803

Start date

Apr 1, 2022

Status verified date

Mar, 2026

Completion date

Mar 31, 2027

Anticipated

Primary completion date

Sep 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

-Veterans who have undergone total knee arthroplasty who present for outpatient rehabilitation treatment at the participating clinics within three weeks of surgery.

Exclusion Criteria:

  • postoperative rehabilitation treatment received in the home health or skilled nursing
  • age < 40 or >90

Study Design

Enrollment

200 participants

Anticipated

Interventions and Outcome Measures

Arms

Control cohort

The investigators will collect outcomes for 100 Veterans treated with usual care rehabilitation after total knee arthroplasty. Data will be collected at all participating clinical locations. Data collection for these Veterans will precede data collection for the intervention cohort.

Intervention cohort

The investigators will implement the clinical decision support tool in all participating clinic locations. We will collect outcomes for 100 Veterans treated in rehabilitation with use of the clinical decision support tool. Data collection for these Veterans will occur after data collection is complete for the Control cohort.

Interventions

Clinical decision support tool (CDS tool)

The investigators will integrate the CDS tool into clinical practice at each participating clinic after data collection for the Control cohort is complete. All physical therapists at the participating clinic locations will use the CDS tool to inform rehabilitation decision making for Veterans with total knee arthroplasty. The CDS tool will provide personalized information regarding each Veterans' recovery in addition to personalized visit utilization guidelines. Clinicians will use the CDS tool with Veterans at their initial postoperative visits and every 2weeks throughout their course of care thereafter.

Primary outcome measure

  • Knee Injury and Osteoarthritis Outcome - Joint Replacement (KOOS, JR) [ Time Frame: Change in KOOS Jr from preop (baseline) to postop (90 days after TKA surgery) ]
  • Outpatient Physical Therapy Visit Utilization [ Time Frame: Postoperative day 90 ]

Central Contacts and Locations

Central contacts

Jennifer E Stevens-Lapsley, PhD

(303) 949-9304Jennifer.Stevens-Lapsley@va.gov

Amy L Peters

(720) 261-9774Amy.Peters3@va.gov

Locations

Rocky Mountain Regional VA Medical Center, Aurora, CO

Recruiting

Aurora, Colorado, United States, 80045-7211

Contacts

Jennifer E Stevens-Lapsley, PhD

303-949-9304Jennifer.Stevens-Lapsley@va.gov

Amy L Peters

(720) 261-9774Amy.Peters3@va.gov

Principal Investigator:

Jennifer E. Stevens-Lapsley, PhD

VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

Recruiting

Pittsburgh, Pennsylvania, United States, 15240

Contacts

Brad Krushinski

(41-2) -3110brad.krushinski@va.gov

Ann Reppermund

(412)5187648ann.reppermund@va.gov

More Information

Sponsor

VA Office of Research and Development

Last update posted

Mar 25, 2026

Last verified

Mar, 2026

Keywords

  • total knee arthroplasty
  • patient-centered care
  • precision medicine

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by VA Office of Research and Development on 2026-03-25.