Recruiting

Music Therapy

Sponsor:

Johns Hopkins University

Code:

NCT05289934

Conditions

Epilepsy

Eligibility Criteria

Sex: All

Age: 4 - 17

Healthy Volunteers: Not accepted

Interventions

Music Stimuli

Study Details

Brief summary:

This research is being done to determine if Mozart music and/or age-appropriate music can reduce the frequency of seizures and epileptiform discharges.

Conditions

Epilepsy

Study ID

NCT05289934

Start date

Apr 22, 2023

Status verified date

Mar, 2026

Completion date

Mar 1, 2027

Anticipated

Primary completion date

Mar 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 4 - 17

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Children (age: 4 - 17 years old) who stay at Epilepsy Monitoring Units (EMU) up to 7 days may join.

Exclusion Criteria:

  • Non-English Speaking

Study Design

Enrollment

10 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Children with Epilepsy

Children (age: 4- 17 years old) will participate in this study, and they will listen to Mozart K.448 (1st movement) and instrumental age-appropriate song with 10 minutes wash out in between, each lasting up to 9 minutes in the daytime (between 1-5 pm). The music stimuli will be randomly played in 2 to 7 days during the EMU stay (average 4 days). Music will be delivered via single-use earbuds.

Interventions

Music Stimuli

Nine-minute-long Mozart K.448 (1st movement) and instrumental age-appropriate songs will be played via single-use earbuds with 10 minutes wash-out in between music stimuli.

Primary outcome measure

  • Change in the frequency of epileptiform discharges (number of spikes) [ Time Frame: Epilepsy Monitoring Units Stay (up to Day 7) ]
  • Change in the frequency of epileptiform discharges (number of seconds with spikes) [ Time Frame: Epilepsy Monitoring Units Stay (up to Day 7) ]

Central Contacts and Locations

Central contacts

Sarah Kelley, MD

4109559100saminof1@jhmi.edu

Locations

Johns Hopkins School of Medicine

Recruiting

Baltimore, Maryland, United States, 21205

Contacts

Sarah Kelley, MD

410-955-9100saminof1@jhmi.edu

More Information

Sponsor

Johns Hopkins University

Last update posted

Mar 6, 2026

Last verified

Mar, 2026

Keywords

  • Epilepsy
  • Electroencephalography (EEG)
  • Music

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Johns Hopkins University on 2026-03-06.